Wong Duo Wai-Chi, Wang Yan, Chen Tony Lin-Wei, Yan Fei, Peng Yinghu, Tan Qitao, Ni Ming, Leung Aaron Kam-Lun, Zhang Ming
Department of Biomedical Engineering, Faculty of Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, China.
Front Bioeng Biotechnol. 2020 Sep 8;8:571192. doi: 10.3389/fbioe.2020.571192. eCollection 2020.
Hallux valgus is a common foot problem affecting nearly one in every four adults. Generalized ligament laxity was proposed as the intrinsic cause or risk factor toward the development of the deformity which was difficult to be investigated by cohort clinical trials. Herein, we aimed to evaluate the isolated influence of generalized ligament laxity on the deterioration using computer simulation (finite element analysis). We reconstructed a computational foot model from a mild hallux valgus participant and conducted a gait analysis to drive the simulation of walking. Through parametric analysis, the stiffness of the ligaments was impoverished at different degrees to resemble different levels of generalized ligament laxity. Our simulation study reported that generalized ligament laxity deteriorated hallux valgus by impairing the load-bearing capacity of the first metatarsal, inducing higher deforming force, moment and malalignment at the first metatarsophalangeal joint. Besides, the deforming moment formed a deteriorating vicious cycle between hallux valgus and forefoot abduction and may result in secondary foot problems, such as flatfoot. However, the metatarsocuneiform joint did not show a worsening trend possibly due to the overriding forefoot abduction. Controlling the deforming load shall be prioritized over the correction of angles to mitigate deterioration or recurrence after surgery.
拇外翻是一种常见的足部问题,几乎每四个成年人中就有一人受其影响。广义韧带松弛被认为是导致该畸形发展的内在原因或风险因素,而队列临床试验难以对此进行研究。在此,我们旨在使用计算机模拟(有限元分析)评估广义韧带松弛对病情恶化的单独影响。我们从一名轻度拇外翻参与者重建了一个足部计算模型,并进行了步态分析以驱动步行模拟。通过参数分析,不同程度地降低韧带刚度以模拟不同水平的广义韧带松弛。我们的模拟研究表明,广义韧带松弛通过损害第一跖骨的承重能力,在第一跖趾关节处诱发更高的变形力、力矩和排列不齐,从而使拇外翻恶化。此外,变形力矩在拇外翻和前足外展之间形成了一个恶化的恶性循环,并可能导致继发性足部问题,如扁平足。然而,跖楔关节可能由于前足外展占主导而未显示出恶化趋势。控制变形负荷应优先于角度矫正,以减轻手术后的病情恶化或复发。