Tan Fen, Wang Kaige, Liu Jiasheng, Liu Dan, Luo Jianfei, Zhou Rui
Department of Pulmonary and Critical Care Medicine, The Second Xiangya Hospital, Respiratory Disease Research Institute of Hunan Province, Central South University, Changsha, China.
Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Front Med (Lausanne). 2020 Aug 18;7:547. doi: 10.3389/fmed.2020.00547. eCollection 2020.
We report the clinical characteristics, viral shedding duration, and contact tracing for asymptomatic carriers of SARS-CoV-2 in Wuhan, China. The asymptomatic carriers were relatively young (median age: 34.5 years). Chest computed tomography showed no abnormalities. The nasopharyngeal swab was an optimum specimen for RNA testing. The median viral shedding duration was 11.5 days. Notably, 2 months of viral shedding duration were reported in two nurses, which was much longer than previously reported or than usually thought. The transmissibility of SARS-CoV-2 by asymptomatic carriers during the studied period in Wuhan appeared to be weak. Only one patient (1/12) was found to have transmitted the virus to another person. Early asymptomatic carrier detection, isolation, and contact tracing could be useful to mitigate the spread of the disease.
我们报告了中国武汉新冠病毒无症状感染者的临床特征、病毒 shedding 持续时间及接触者追踪情况。无症状感染者相对年轻（中位年龄：34.5 岁）。胸部计算机断层扫描显示无异常。鼻咽拭子是 RNA 检测的最佳标本。病毒 shedding 持续时间的中位数为 11.5 天。值得注意的是，两名护士报告的病毒 shedding 持续时间为 2 个月，这比之前报道的或通常认为的要长得多。在武汉研究期间，无症状感染者传播新冠病毒的能力似乎较弱。仅发现 1 例患者（1/12）将病毒传播给了另一人。早期发现无症状感染者、隔离及接触者追踪对于减轻疾病传播可能有用。 （注：“shedding”在这里可能是指病毒排出之类的意思，文中未明确给出更准确中文释义）
