Urology Department, Firoozgar Hospital, Iran University of Medical Sciences, Tehran.
Arch Ital Urol Androl. 2020 Oct 2;92(3). doi: 10.4081/aiua.2020.3.259.
To estimate the duration of time required following varicocelectomy to wait for the improvements of semen parameters. Therefore, we characterized the changes with the time in sperm parameters in men after varicocelectomy.
In this prospective cohort study we included consecutively observed men who underwent varicocelectomy between September 2017 and September 2018 in a referral academic hospital. Clinical data of the patients, as well as their semen parameters, were measured before surgery and at 3 and 6 months afterward.
In this study, a total of 100 men with average age of 29.5 ± 6.2 years were included. Mean sperm concentration and sperm motility significantly improved by 3 (p < 0.05), but not by 6 months following varicocelectomy. The semen volume and sperm with normal morphology were the same before and after surgery (p > 0.05). There was no statistically significant difference in the improvement of semen parameters when comparing 6 months to 3 months postoperatively (p > 0.05).
Sperm parameters (concentration and motility) improve by 3 months after varicocelectomy without further improvements. Consequently, physicians should decide quickly after 3-month of varicocelectomy if surgery has been not helpful and then plan other therapies, like assisted reproductive technology (ART) for managing infertility in couples.
评估精索静脉曲张手术后等待精液参数改善所需的时间。因此，我们对精索静脉曲张手术后男性精液参数随时间的变化特征进行了研究。
本前瞻性队列研究纳入了 2017 年 9 月至 2018 年 9 月期间在一家学术转诊医院接受精索静脉曲张手术的连续观察男性。术前和术后 3 个月和 6 个月测量患者的临床数据和精液参数。
本研究共纳入 100 名平均年龄 29.5 ± 6.2 岁的男性。精索静脉曲张手术后 3 个月，精子浓度和精子活力显著提高（p < 0.05），但 6 个月后无明显改善。手术前后精液量和正常形态精子无明显差异（p > 0.05）。术后 6 个月与 3 个月相比，精液参数改善无统计学差异（p > 0.05）。
精索静脉曲张手术后 3 个月精子参数（浓度和活力）改善，之后无进一步改善。因此，医生应在精索静脉曲张手术后 3 个月后迅速决定手术是否有效，然后计划其他治疗方法，如辅助生殖技术（ART）来治疗夫妇不孕。
