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小儿肺曲霉菌球病的外科治疗:3 例报告。

Surgical treatment of pulmonary aspergilloma in pediatric patients: report of 3 cases.

机构信息

Pediatric Surgery Department. La Fe University and Polytechnic Hospital, Valencia (Spain).

出版信息

Cir Pediatr. 2020 Oct 1;33(4):193-199.

Abstract

OBJECTIVE

To describe our experience in the surgical management of pulmonary aspergilloma (PA) and review surgery's role in PA treatment in pediatric patients.

MATERIAL AND METHODS

A descriptive study of patients diagnosed with PA undergoing surgical resection from 2017 to 2019 was carried out. A review of pediatric studies mentioning "aspergilloma", "surgical", and "treatment" was performed.

RESULTS

During the study period, 3 patients with single PA aged 18 months old, 3 years old, and 13 years old underwent surgery. All of them had leukemia and little or no response to aspergilloma medical treatment. In all patients, the procedure was initiated using the thoracoscopic route, but conversion into thoracotomy was required in two cases. In all three cases, pulmonary segmentectomy was carried out with complete PA removal, without severe intraoperative or postoperative complications. No pulmonary recurrence was observed after 30-, 34-, and 16-month follow-up, respectively.

CONCLUSIONS

PA surgical resection is a feasible alternative in pediatric patients with a poor antifungal treatment response or related complications.

摘要

目的

描述我们在肺曲霉菌病(PA)的外科治疗方面的经验,并回顾手术在儿科患者 PA 治疗中的作用。

材料与方法

对 2017 年至 2019 年期间接受手术切除的确诊为 PA 的患者进行描述性研究。回顾了提到“曲霉菌病”、“外科”和“治疗”的儿科研究。

结果

在研究期间,3 名患有单发 PA 的患儿年龄分别为 18 个月、3 岁和 13 岁,均患有白血病,对曲霉菌病的药物治疗反应不佳或无反应。所有患者均采用胸腔镜入路开始手术,但有两例需要转为开胸手术。在所有 3 例患者中,均进行了肺段切除术,完全切除了 PA,术中及术后均无严重并发症。分别在 30、34 和 16 个月的随访中,均未观察到肺部复发。

结论

对于抗真菌治疗反应差或相关并发症的儿科患者,PA 手术切除是一种可行的选择。

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