提高亨廷顿病患者 DriveSafe DriveAware 的临床实用性。

Enhancing the Clinical Utility of DriveSafe DriveAware for People with Huntington's Disease.

机构信息

School of Psychological Sciences and the Turner Institute for Brain and Mental Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.

Calvary Health Care Bethlehem, State-wide Progressive Neurological Disease Service, Caulfield South, Victoria, Australia.

出版信息

J Huntingtons Dis. 2020;9(4):353-357. doi: 10.3233/JHD-200420.

DOI:10.3233/JHD-200420

PMID:33016891

Abstract

DriveSafe DriveAware (DSDA) is a cognitive screening tool assessing driving safety. Previously, we found DSDA categorised some HD participants as 'likely to pass' on-road assessments, despite displaying cognitive impairments in domains known to impact driving. As processing speed is affected early in HD, we examined whether DSDA completion time could provide supplementary cognitive information to support clinical decision-making. The HD group completed subtests significantly slower than controls, and completion times correlated with cognitive functions essential for driving. Considering DSDA completion time may tailor the assessment for people with HD so that it is more reflective of HD-related cognitive functioning.

摘要

驾车安全意识测验（DSDA）是一种认知筛查工具，用于评估驾驶安全性。此前，我们发现 DSDA 将一些 HD 参与者归类为“可能通过”路考评估，尽管他们在已知会影响驾驶的认知领域存在障碍。由于处理速度在 HD 中很早就受到影响，我们研究了 DSDA 的完成时间是否可以提供额外的认知信息，以支持临床决策。HD 组完成子测试的速度明显慢于对照组，并且完成时间与驾驶所必需的认知功能相关。考虑到 DSDA 的完成时间可能会根据 HD 患者的情况调整评估，使其更能反映与 HD 相关的认知功能。