Orter Stefan, Mostl Stefan, Bachler Martin, Hoffmann Fabian, Kaniusas Eugenijus, Reisinger Michaela, Wassertheurer Siegfried, Tank Jens, Hametner Bernhard
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2715-2718. doi: 10.1109/EMBC44109.2020.9176275.
Arterial stiffness is an important indicator for vascular aging and an independent predictor for cardiovascular diseases. During space flights or simulated space flights by prolonged head-down tilt bed rest, major cardiovascular alterations occur. However, the changes in arterial stiffness are not fully understood yet. Thus, we aimed to develop a setup for the measurement of arterial stiffness during prolonged head-down tilt bed rest, which incorporates several combinations of biosignals and measurement locations for the determination of pulse transit times. By performing measurements using this setup on female and male subjects, we intend to deepen the understanding of changes in arterial stiffness during prolonged head-down tilt bed rest. This work describes and visualizes the complete setup as well as our measurement protocols and algorithms used. The result section shows the successful recording of baseline signals before the bed rest study and visualizes the synchronized recordings of pulse waves measured on different sides of the body. Thus, it is feasible to use the presented setup in bed rest studies.
动脉僵硬度是血管老化的重要指标，也是心血管疾病的独立预测因子。在太空飞行或通过长时间头低位卧床休息进行模拟太空飞行期间，会发生主要的心血管改变。然而，动脉僵硬度的变化尚未完全明确。因此，我们旨在开发一种用于在长时间头低位卧床休息期间测量动脉僵硬度的装置，该装置结合了多种生物信号和测量位置组合以确定脉搏传输时间。通过使用此装置对女性和男性受试者进行测量，我们旨在加深对长时间头低位卧床休息期间动脉僵硬度变化的理解。本文描述并展示了完整的装置以及我们使用的测量方案和算法。结果部分展示了卧床休息研究前基线信号的成功记录，并呈现了在身体不同部位测量的脉搏波同步记录。因此，在所呈现的卧床休息研究中使用该装置是可行的。
