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浓缩 Bioshell 氧化钙水在表面和皮肤消毒中的应用对病原微生物的安全性。

Safety of Concentrated Bioshell Calcium Oxide Water Application for Surface and Skin Disinfections against Pathogenic Microbes.

机构信息

Division of Biomedical Engineering, National Defense Medical College Research Institute, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.

Department of Oral and Maxillofacial Surgery, National Defense Medical College Hospital, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.

出版信息

Molecules. 2020 Oct 1;25(19):4502. doi: 10.3390/molecules25194502.

DOI:10.3390/molecules25194502
PMID:33019606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7582750/
Abstract

Immediately post-production, commercially available bioshell calcium oxide (BiSCaO) water is colorless, transparent, and strongly alkaline (pH 12.8), and is known to possess deodorizing properties and broad microbicidal activity. However, BiSCaO Water may represent a serious safety risk to the living body, given the strong alkalinity. This study aimed to investigate the safety of BiSCaO Water for use as an antiseptic/disinfectant despite concerns regarding its high alkalinity. The change over time in pH of BiSCaO Water was measured during air contact (stirring BiSCaO Water in ambient air). When sprayed on metal, plastic, wood piece, paper, and skin surfaces, the pH of BiSCaO Water decreased rapidly, providing a white powder coating upon drying. Scanning electron microscopy images, energy dispersive X-ray elemental mapping, and X-ray diffractograms showed that the dried powder residues of BiSCaO Water were composed primarily of calcium carbonate. These results suggested that BiSCaO Water is a potent reagent that may overcome the obstacles of being strongly alkaline, making this material appropriate for use in disinfection against pathogenic microbes.

摘要

市售生物壳氧化钙（BiSCaO）水在生产后立即呈无色透明强碱性（pH 值 12.8），具有除臭性能和广谱杀菌活性。然而，鉴于其强碱性，BiSCaO 水可能对生物体构成严重的安全风险。本研究旨在探讨 BiSCaO 水作为消毒剂/防腐剂的安全性，尽管人们对其高碱性存在担忧。通过在空气中接触（在环境空气中搅拌 BiSCaO 水）来测量 BiSCaO 水的 pH 值随时间的变化。当 BiSCaO 水喷在金属、塑料、木块、纸张和皮肤表面上时，其 pH 值迅速下降，干燥后形成白色粉末涂层。扫描电子显微镜图像、能量色散 X 射线元素映射和 X 射线衍射图表明，BiSCaO 水的干燥粉末残留物主要由碳酸钙组成。这些结果表明，BiSCaO 水是一种有效试剂，可能克服强碱性的障碍，使这种材料适合用于消毒对抗致病微生物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/c5eda1f0bb00/molecules-25-04502-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/70a7a3842651/molecules-25-04502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/116fc188526e/molecules-25-04502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/acf0e287150c/molecules-25-04502-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/ca9f4f91c1a7/molecules-25-04502-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/e5bbf66b109b/molecules-25-04502-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/4b862a41323a/molecules-25-04502-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/c5eda1f0bb00/molecules-25-04502-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/70a7a3842651/molecules-25-04502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/116fc188526e/molecules-25-04502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/acf0e287150c/molecules-25-04502-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/ca9f4f91c1a7/molecules-25-04502-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/e5bbf66b109b/molecules-25-04502-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/4b862a41323a/molecules-25-04502-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37ac/7582750/c5eda1f0bb00/molecules-25-04502-g007.jpg

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