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漏斗形对阿拉伯置管、麦克唐纳宫颈环扎或早期完全宫颈闭塞术(ETCO)治疗的自发性早产患者二级预防的影响。

The impact of funneling shape on the secondary prevention of spontaneous preterm birth in patients treated with either an Arabin pessary, McDonald cerclage or early total cervical occlusion (ETCO).

机构信息

Department Of Obstetrics and Gynecology, Centre for Ultrasound and Prenatal Medicine, Buergerhospital and Clementine Children's Hospital Frankfurt a.M, Dr. Senckenberg Foundation and Johann-Wolfgang-Goethe University of Frankfurt, Frankfurt, Germany.

Faculty of Medicine, Philipps University of Marburg, Marburg, Germany.

出版信息

J Matern Fetal Neonatal Med. 2022 Sep;35(17):3309-3317. doi: 10.1080/14767058.2020.1818209. Epub 2020 Oct 5.

Abstract

OBJECTIVE

Cervical funneling is associated with spontaneous preterm birth (sPTB). The aim of this analysis was to assess the relationship between funneling shape and the response to the McDonald cerclage, the Arabin pessary and the early total cervical occlusion (ETCO).

METHODS

We retrospectively analyzed data of 312 randomly selected singleton pregnancies with cervical shortening <25 mm or normal cervical length and evaluated them according to the progression of funneling: control group ( = 46), cervical shortening without funneling ( = 107), V-shaped funneling ( = 68), U-shaped funneling ( = 47), and prolapse of the amniotic sac ( = 44). We evaluated sPTB rates <34, <28, <32, and <37 weeks as well as prolongation of gestation and birthweight.

RESULTS

Regarding the rate of sPTB <34 weeks there was no statistical significance in either of the comparisons between control group and each of the four risk groups. Regarding prolongation of gestation we demonstrated a statistical significance for all risk groups compared to the control group (all  < .05) with the lowest prolongation rate noted in the group with amnion prolapse and the highest in the group with isolated cervical shortening without funneling. Similarly, progression of funnel shape resulted in an absolute decrease of birthweight for all risk groups compared to the control group, albeit not significant for the group with U-shaped funneling ( = .1058).

CONCLUSION

Independent of the treatment, there was a significant impact of funneling shape on pregnancy duration and birthweight.

摘要

目的

宫颈漏斗与自发性早产(sPTB)有关。本分析的目的是评估漏斗形状与 McDonald 环扎术、Arabin 栓剂和早期完全宫颈闭塞(ETCO)反应之间的关系。

方法

我们回顾性分析了 312 例随机选择的宫颈缩短<25mm 或正常宫颈长度的单胎妊娠数据,并根据漏斗进展对其进行评估:对照组(n=46)、无漏斗状宫颈缩短(n=107)、V 形漏斗(n=68)、U 形漏斗(n=47)和羊膜囊脱垂(n=44)。我们评估了 sPTB 发生率<34 周、<28 周、<32 周和<37 周,以及妊娠延长和出生体重。

结果

关于 sPTB <34 周的发生率,对照组与四个风险组中的任何一组之间的比较均无统计学意义。关于妊娠延长,我们发现所有风险组与对照组相比均有统计学意义(均<.05),其中羊膜囊脱垂组的妊娠延长率最低,而无漏斗状宫颈缩短组的妊娠延长率最高。同样,与对照组相比,漏斗形状的进展导致所有风险组的出生体重绝对下降,尽管 U 形漏斗组没有显著差异(=.1058)。

结论

无论治疗如何,漏斗形状对妊娠持续时间和出生体重都有显著影响。

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