Department of Obstetrics and Gynecology, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Medical Informatics Laboratory, Medical School, Democritus University of Thrace, 68100 Alexandroupolis, Greece.
Int J Environ Res Public Health. 2018 Apr 18;15(4):791. doi: 10.3390/ijerph15040791.
Preterm labor is one of the most significant obstetric problems associated with high rate of actual and long-term perinatal complications. Despite the creation of scoring systems, uterine activity monitoring, cervical ultrasound and several biochemical markers, the prediction and prevention of preterm labor is still a matter of concern. The aim of this study was to examine cervical findings for the prediction and the comparative use of Arabin pessary or cerclage for the prevention of preterm birth in asymptomatic women with high risk factors for preterm labor.
The study group was composed of singleton pregnancies (spontaneously conceived) with high risk factors for preterm labor. Cervical length, dilatation of the internal cervical os and funneling, were estimated with transvaginal ultrasound during the first and the second trimesters of pregnancy.
Cervical funneling, during the second trimester of pregnancy, was the most significant factor for the prediction of preterm labor. The use of Arabin cervical pessary was found to be more effective than cerclage in the prolongation of pregnancy.
In women at risk for preterm labor, the detection of cervical funneling in the second trimester of pregnancy may help to predict preterm labor and to apply the appropriate treatment for its prevention. Although the use of cervical pessary was found to be more effective than cerclage, more studies are needed to classify the effectiveness of different methods for such prevention.
早产是与高发生率实际和长期围产期并发症相关的最重要产科问题之一。尽管创建了评分系统、子宫活动监测、宫颈超声和几种生化标志物,但早产的预测和预防仍然是一个关注的问题。本研究旨在检查宫颈发现,以预测和比较阿拉伯宫颈栓剂或环扎术在有早产高危因素的无症状妇女中的应用,以预防早产。
研究组由高危早产因素的单胎妊娠(自然受孕)组成。在妊娠的第一和第二个三个月期间,通过阴道超声估计宫颈长度、宫颈内口扩张和漏斗形成。
妊娠中期宫颈漏斗形成是预测早产的最重要因素。阿拉伯宫颈栓剂的使用比环扎术更能延长妊娠时间。
在有早产风险的妇女中,妊娠中期宫颈漏斗形成的检测可能有助于预测早产,并应用适当的治疗方法预防早产。尽管宫颈栓剂的使用被发现比环扎术更有效,但需要更多的研究来对不同预防方法的有效性进行分类。