Department of Psychiatry and Behavioral Sciences (Thompson, Mikolajewski), Department of Microbiology and Immunology (Smither), and Department of Pathology and Laboratory Medicine (Lin, Tian), Tulane University School of Medicine, New Orleans; Tulane University of School of Public Health and Tropical Medicine, New Orleans (Kissinger, McCrossen); LaCATS-Clinical Translational Unit, New Orleans (Chamarthi).
Psychiatr Serv. 2020 Dec 1;71(12):1285-1287. doi: 10.1176/appi.ps.202000270. Epub 2020 Oct 6.
This study aimed to explore the transmission of COVID-19 in a U.S. state psychiatric hospital setting.
Symptomatic and asymptomatic patients were tested throughout a large psychiatric hospital to determine penetrance. The hospital followed initial Centers for Disease Control and Prevention (CDC) guidelines.
Seventy-eight percent (N=51 of 65) of tested patients in the building where the first positive patient was housed (building zero) tested positive for COVID-19. Eighty-eight percent (N=14 of 16) of tested asymptomatic patients in building zero were positive, compared with 12% (N=6 of 51) of randomly selected asymptomatic patients in a sample from the rest of the hospital.
A high percentage of patients can become positive for COVID-19 despite following initial CDC guidelines. As such, use of masks by all patients in close-quarter settings prior to the first positive case appears warranted. Recent CDC guidelines align with this strategy.
本研究旨在探讨美国州立精神病院环境中 COVID-19 的传播情况。
对大型精神病院内的有症状和无症状患者进行了全面检测，以确定其感染率。该医院遵循了最初的疾病控制与预防中心（CDC）指南。
在首例阳性患者所在的建筑物（零号楼）中接受检测的患者中，有 78%（65 名患者中有 51 名）检测呈 COVID-19 阳性。零号楼中 88%（16 名无症状患者中有 14 名）的检测呈阳性，而在医院其他区域随机抽取的 51 名无症状患者中，仅有 12%（6 名）检测呈阳性。
尽管遵循了最初的 CDC 指南，但仍有很大比例的患者会检测出 COVID-19 阳性。因此，在首例阳性病例之前，在密切接触环境中，所有患者使用口罩似乎是合理的。最近的 CDC 指南与这一策略一致。
