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州立精神病院 COVID-19 患者的流行病学研究:早期 CDC 指南的高患病率。

An Epidemiologic Study of COVID-19 Patients in a State Psychiatric Hospital: High Penetrance With Early CDC Guidelines.

机构信息

Department of Psychiatry and Behavioral Sciences (Thompson, Mikolajewski), Department of Microbiology and Immunology (Smither), and Department of Pathology and Laboratory Medicine (Lin, Tian), Tulane University School of Medicine, New Orleans; Tulane University of School of Public Health and Tropical Medicine, New Orleans (Kissinger, McCrossen); LaCATS-Clinical Translational Unit, New Orleans (Chamarthi).

出版信息

Psychiatr Serv. 2020 Dec 1;71(12):1285-1287. doi: 10.1176/appi.ps.202000270. Epub 2020 Oct 6.

Abstract

OBJECTIVE

This study aimed to explore the transmission of COVID-19 in a U.S. state psychiatric hospital setting.

METHODS

Symptomatic and asymptomatic patients were tested throughout a large psychiatric hospital to determine penetrance. The hospital followed initial Centers for Disease Control and Prevention (CDC) guidelines.

RESULTS

Seventy-eight percent (N=51 of 65) of tested patients in the building where the first positive patient was housed (building zero) tested positive for COVID-19. Eighty-eight percent (N=14 of 16) of tested asymptomatic patients in building zero were positive, compared with 12% (N=6 of 51) of randomly selected asymptomatic patients in a sample from the rest of the hospital.

CONCLUSIONS

A high percentage of patients can become positive for COVID-19 despite following initial CDC guidelines. As such, use of masks by all patients in close-quarter settings prior to the first positive case appears warranted. Recent CDC guidelines align with this strategy.

摘要

目的

本研究旨在探讨美国州立精神病院环境中 COVID-19 的传播情况。

方法

对大型精神病院内的有症状和无症状患者进行了全面检测,以确定其感染率。该医院遵循了最初的疾病控制与预防中心(CDC)指南。

结果

在首例阳性患者所在的建筑物(零号楼)中接受检测的患者中,有 78%(65 名患者中有 51 名)检测呈 COVID-19 阳性。零号楼中 88%(16 名无症状患者中有 14 名)的检测呈阳性,而在医院其他区域随机抽取的 51 名无症状患者中,仅有 12%(6 名)检测呈阳性。

结论

尽管遵循了最初的 CDC 指南,但仍有很大比例的患者会检测出 COVID-19 阳性。因此,在首例阳性病例之前,在密切接触环境中,所有患者使用口罩似乎是合理的。最近的 CDC 指南与这一策略一致。

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