Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Louisville, Louisville, KY; Department of Infection Control and Prevention, University of Louisville Hospital (UofL Health), Louisville, KY.
Department of Infection Control and Prevention, University of Louisville Hospital (UofL Health), Louisville, KY.
Am J Infect Control. 2021 Mar;49(3):281-285. doi: 10.1016/j.ajic.2021.01.005. Epub 2021 Jan 9.
The proportion of positive patients admitted to acute-care hospitals for reasons other than coronavirus disease-19 (COVID-19) is unknown. These patients potentially put other patients and healthcare workers at risk of infection.
The objective of this study was to define the proportion of asymptomatic patients admitted with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Secondary objectives were to define the positivity rate, reasons for admission, and the geographic distribution in the region.
Universal surveillance testing for SARS-CoV-2 was performed on patients admitted to this hospital over a 12-week period from April 9, 2020 to July 1, 2020. Positive patients were categorized as either symptomatic or asymptomatic as defined by the 11 criteria per the Centers for Disease Control and Prevention. The positivity rate, proportion with and without symptoms, reasons for admission, and geographic distribution in the region were recorded.
The positivity rate ranged from 0.8% to 6.2%. The proportion of asymptomatic patients with SARS-CoV-2 was 37%. Asymptomatic patients primarily presented to the hospital because of either trauma or labor. Some clusters in the region were identified of both symptomatic and asymptomatic patients.
The proportion of asymptomatic patients admitted with SARS-CoV-2 was significant. Identifying and isolating asymptomatic patients likely prevented exposure and development of hospital-acquired COVID-19 cases among healthcare workers and other patients, supporting the universal surveillance of all admitted patients.
因非 2019 冠状病毒病（COVID-19）而入住急性护理医院的阳性患者比例未知。这些患者可能使其他患者和医护人员面临感染风险。
本研究旨在确定无症状患者因严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）而入院的比例。次要目标是定义阳性率、入院原因和该地区的地理分布。
在 2020 年 4 月 9 日至 7 月 1 日的 12 周期间，对入住该院的患者进行了 SARS-CoV-2 的普遍监测检测。阳性患者根据疾病控制与预防中心的 11 项标准，分为有症状或无症状。记录阳性率、有症状和无症状患者的比例、入院原因和该地区的地理分布。
阳性率在 0.8%至 6.2%之间。SARS-CoV-2 无症状患者的比例为 37%。无症状患者主要因创伤或分娩而到医院就诊。该地区发现了一些有症状和无症状患者的集群。
因 SARS-CoV-2 而住院的无症状患者比例较高。识别和隔离无症状患者可能防止了医护人员和其他患者中 COVID-19 医院获得性感染的发生，支持对所有入院患者进行普遍监测。
