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Molecular forms of serum insulin-like growth factor (IGF)-binding proteins in man: relationships with growth hormone and IGFs and physiological significance.人血清胰岛素样生长因子（IGF）结合蛋白的分子形式：与生长激素和IGF的关系及生理意义。
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本文引用的文献

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Pitfalls in the somatomedin-C radioimmunoassay.
J Clin Endocrinol Metab. 1982 May;54(5):1084-6. doi: 10.1210/jcem-54-5-1084.
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Inhibition of terminal axonal sprouting by serum from patients with amyotrophic lateral sclerosis.
N Engl J Med. 1984 Oct 11;311(15):933-9. doi: 10.1056/NEJM198410113111501.
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Stimulation and inhibition of myoblast differentiation by hormones.激素对成肌细胞分化的刺激与抑制作用。
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Insulin-like growth factor I/somatomedin C (IGF-I/Sm C): comparison of natural, solid phase synthetic and recombinant DNA analog peptides in two radioligand assays.胰岛素样生长因子I/生长调节素C（IGF-I/Sm C）：在两种放射性配体分析中天然、固相合成及重组DNA类似肽的比较
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Somatomedin activity in disorders of nutrition and metabolism.
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Somatomedins (first of two parts).生长调节素（两部分中的第一部分）。
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7
Distinct biologically active receptors for insulin, insulin-like growth factor I, and insulin-like growth factor II in cultured skeletal muscle cells.培养的骨骼肌细胞中胰岛素、胰岛素样生长因子I和胰岛素样生长因子II的不同生物活性受体。
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Estimation of somatomedin-C levels in normals and patients with pituitary disease by radioimmunoassay.采用放射免疫分析法测定正常人和垂体疾病患者的生长调节素C水平。
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Insulin and growth hormone: regulators of growth with particular reference to muscle.胰岛素与生长激素：特别是对肌肉而言的生长调节因子。
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肌萎缩侧索硬化症患者的血清胰岛素样生长因子-I水平

Serum insulin-like growth factor-I levels in amyotrophic lateral sclerosis.

作者信息

Braunstein G D, Reviczky A L

出版信息

J Neurol Neurosurg Psychiatry. 1987 Jun;50(6):792-4. doi: 10.1136/jnnp.50.6.792.

DOI:10.1136/jnnp.50.6.792
PMID:3302111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1032090/
Abstract

The serum concentrations of the myotrophic hormone insulin-like growth factor-I (IGF-I) in 23 patients with amyotrophic lateral sclerosis were not significantly different from those found in the sera of 13 control patients. There was no difference in binding of 125I-IGF-I by serum from patients with amyotrophic lateral sclerosis in comparison with that found in the controls. These results indicate that immunoreactive IGF-I concentrations are normal in patients with amyotrophic lateral sclerosis and that such patients do not have significant antibodies binding their endogenous IGF-I.

摘要

23例肌萎缩侧索硬化患者血清中的肌营养激素胰岛素样生长因子-I（IGF-I）浓度与13例对照患者血清中的浓度无显著差异。与对照组相比，肌萎缩侧索硬化患者血清对125I-IGF-I的结合无差异。这些结果表明，肌萎缩侧索硬化患者免疫反应性IGF-I浓度正常，且此类患者不存在结合其内源性IGF-I的显著抗体。