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伏隔核与额顶叶网络的功能连接可预测美国儿童随后体重指数的变化。

Nucleus Accumbens Functional Connectivity with the Frontoparietal Network Predicts Subsequent Change in Body Mass Index for American Children.

作者信息

Assari Shervin, Boyce Shanika, Bazargan Mohsen

机构信息

Department of Family Medicine, Charles Drew University, Los Angeles, CA 90059, USA.

Department of Urban Public Health, Charles Drew University, Los Angeles, CA 90059, USA;.

出版信息

Brain Sci. 2020 Oct 3;10(10):703. doi: 10.3390/brainsci10100703.

DOI:10.3390/brainsci10100703
PMID:33022949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7600639/
Abstract

The epidemiological observation that NAc functional connectivity is associated with BMI changes in children is an extension of well-controlled laboratory studies that have established the role of the NAc in the brain reward processing. More research is needed on sex differences in the brain regions that contribute to childhood obesity.

摘要

流行病学观察发现,伏隔核功能连接性与儿童体重指数变化相关,这是对精心控制的实验室研究的拓展,这些研究已确定了伏隔核在大脑奖赏处理中的作用。对于导致儿童肥胖的脑区中的性别差异,还需要开展更多研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16b/7600639/4a60c73b4981/brainsci-10-00703-g0A2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16b/7600639/db7bde740db0/brainsci-10-00703-g0A1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16b/7600639/4a60c73b4981/brainsci-10-00703-g0A2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16b/7600639/db7bde740db0/brainsci-10-00703-g0A1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b16b/7600639/4a60c73b4981/brainsci-10-00703-g0A2.jpg

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本文引用的文献

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Multivariate association between brain function and eating disorders using sparse canonical correlation analysis.使用稀疏典型相关分析研究脑功能与饮食失调的多变量关联。
PLoS One. 2020 Aug 12;15(8):e0237511. doi: 10.1371/journal.pone.0237511. eCollection 2020.
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Sex specific effects of "junk-food" diet on calcium permeable AMPA receptors and silent synapses in the nucleus accumbens core.“垃圾食品”饮食对伏隔核核心中钙通透性AMPA受体和沉默突触的性别特异性影响。
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Regional cerebral blood flow at rest in obesity.
儿童和青少年暴食的前驱因素:神经发育,以及超加工食品的潜在贡献。
Nutrients. 2023 Jun 30;15(13):2994. doi: 10.3390/nu15132994.
肥胖患者静息状态下的局部脑血流。
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Stimuli predicting high-calorie reward increase dopamine release and drive approach to food in the absence of homeostatic need.刺激预测高热量奖励会增加多巴胺释放,并在没有体内平衡需求的情况下促使人们接近食物。
Nutr Neurosci. 2022 Mar;25(3):593-602. doi: 10.1080/1028415X.2020.1782613. Epub 2020 Jun 24.
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Altered Interactions Among Resting-State Networks in Individuals with Obesity.肥胖个体静息态网络间相互作用的改变。
Obesity (Silver Spring). 2020 Mar;28(3):601-608. doi: 10.1002/oby.22731.
6
The orexinergic neural pathway from the lateral hypothalamus to the nucleus accumbens and its regulation of palatable food intake.外侧下丘脑至伏隔核的食欲素能神经通路及其对美味食物摄入的调节。
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