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COVID-19 大流行期间经皮冠状动脉介入治疗心肌梗死的发生率和结局。

Incidence and outcome of myocardial infarction treated with percutaneous coronary intervention during COVID-19 pandemic.

机构信息

Department of Cardiology, Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden.

Department of Cardiology, Linköping University, Linköping, Sweden.

出版信息

Heart. 2020 Dec;106(23):1812-1818. doi: 10.1136/heartjnl-2020-317685. Epub 2020 Oct 6.

Abstract

OBJECTIVE

Most reports on the declining incidence of myocardial infarction (MI) during the COVID-19 have either been anecdotal, survey results or geographically limited to areas with lockdowns. We examined the incidence of MI during the COVID-19 pandemic in Sweden, which has remained an open society with a different public health approach fighting COVID-19.

METHODS

We assessed the incidence rate (IR) as well as the incidence rate ratios (IRRs) of all MI referred for coronary angiography in Sweden using the nationwide Swedish Coronary Angiography and Angioplasty Registry (SCAAR), during the COVID-19 pandemic in Sweden (1 March 2020-7 May 2020) in relation to the same days 2015-2019.

RESULTS

A total of 2443 MIs were referred for coronary angiography during the COVID-19 pandemic resulting in an IR 36 MIs/day (204 MIs/100 000 per year) compared with 15 213 MIs during the reference period with an IR of 45 MIs/day (254 MIs/100 000 per year) resulting in IRR of 0.80, 95% CI (0.74 to 0.86), p<0.001. Results were consistent in all investigated patient subgroups, indicating no change in patient category seeking cardiac care. Kaplan-Meier event rates for 7-day case fatality were 439 (2.3%) compared with 37 (2.9%) (HR: 0.81, 95% CI (0.58 to 1.13), p=0.21). Time to percutaneous coronary intervention (PCI) was shorter during the pandemic and PCI was equally performed, indicating no change in quality of care during the pandemic.

CONCLUSION

The COVID-19 pandemic has significantly reduced the incidence of MI referred for invasive treatment strategy. No differences in overall short-term case fatality or quality of care indicators were observed.

摘要

目的

大多数关于 COVID-19 期间心肌梗死(MI)发病率下降的报告要么是轶事报告、调查结果,要么是仅限于实施封锁地区的地域报告。我们在瑞典检查了 COVID-19 大流行期间 MI 的发病率,瑞典一直是一个开放的社会,在抗击 COVID-19 方面采取了不同的公共卫生措施。

方法

我们使用全国瑞典冠状动脉造影和血管成形术登记处(SCAAR)评估了瑞典 COVID-19 大流行期间(2020 年 3 月 1 日至 2020 年 5 月 7 日)所有因 MI 而行冠状动脉造影的发病率(IR)以及发病率比值(IRR),并与同期(2015 年至 2019 年)进行了比较。

结果

在 COVID-19 大流行期间,共有 2443 例 MI 因 MI 而行冠状动脉造影,发病率为 36 例/天(每 10 万人每年 204 例),而在参考期间,共有 15213 例 MI 因 MI 而行冠状动脉造影,发病率为 45 例/天(每 10 万人每年 254 例),IRR 为 0.80,95%CI(0.74 至 0.86),p<0.001。所有调查的患者亚组的结果均一致,表明寻求心脏治疗的患者类别没有变化。7 天病例死亡率的 Kaplan-Meier 事件率为 439(2.3%),而 37(2.9%)(HR:0.81,95%CI(0.58 至 1.13),p=0.21)。大流行期间经皮冠状动脉介入治疗(PCI)的时间更短,且 PCI 的治疗同样得到开展,表明大流行期间的护理质量没有变化。

结论

COVID-19 大流行显著降低了接受侵入性治疗策略的 MI 发病率。未观察到总体短期病死率或护理质量指标的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d845/7677488/507b06b430a7/heartjnl-2020-317685f01.jpg

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