Child and Adolescent Psychiatry Unit, Salvator Hospital, Public Assistance-Marseille Hospitals, Aix-Marseille University, 249 Boulevard Sainte-Marguerite, 13009, Marseille, France.
Institute of Neuroscience Timone, CNRS, Aix-Marseille University, Marseille, France.
Eat Weight Disord. 2021 Aug;26(6):1845-1852. doi: 10.1007/s40519-020-01033-z. Epub 2020 Oct 6.
This retrospective study investigated, for the first time, sleep characteristics in anorexia nervosa (AN) subtypes and the clinical profile in adolescents, as well as the quality of life (QoL) and emotionality in these patients with poor sleep.
The sample included 111 adolescents with AN. First, restrictive AN (ANR) and binge eating/purging AN (ANB/P) groups were compared in terms of self-reported sleep characteristics, sleepiness and chronotype. Second, the clinical profile, QoL, and emotionality of good sleepers (GS) and poor sleepers (PS) were compared.
Compared to the ANR group, participants with ANB/P showed significantly greater sleep disturbances and sleepiness, and also a higher preference for an eveningness chronotype. Results also showed a clinical profile significantly more severe in PS than in GS. After adjustment, only the ANB/P subtype and the EDI-2 ineffectiveness subscale remained significantly linked to poor sleep. Moreover, the QoL was lower and emotionality more negative in PS with respect to GS.
Findings suggest that subjective sleep disturbances may be used as a clinical marker for AN severity and for ANB/P subtype. Importantly, findings suggest that improving sleep quality in adolescents with AN may help managing their ED and their comorbidities, but also improve their QoL.
Level V, descriptive study (evaluation data retrospectively studied).
本回顾性研究首次探讨了厌食症（AN）亚型的睡眠特征以及青少年患者的临床特征，以及这些睡眠不佳患者的生活质量（QoL）和情绪。
该样本包括 111 名患有 AN 的青少年。首先，将限制型 AN（ANR）和暴食/清除型 AN（ANB/P）组在自我报告的睡眠特征、嗜睡和昼夜节律方面进行比较。其次，比较了睡眠良好者（GS）和睡眠不佳者（PS）的临床特征、生活质量和情绪。
与 ANR 组相比，ANB/P 组的睡眠障碍和嗜睡明显更严重，并且更喜欢夜间型昼夜节律。结果还显示 PS 的临床特征明显比 GS 更严重。调整后，只有 ANB/P 亚型和 EDI-2 无效分量表与睡眠不佳显著相关。此外，PS 的生活质量低于 GS，情绪更为消极。
研究结果表明，主观睡眠障碍可能可作为 AN 严重程度和 ANB/P 亚型的临床标志物。重要的是，研究结果表明，改善 AN 青少年的睡眠质量可能有助于治疗他们的 ED 和合并症，还可能提高他们的生活质量。
五级，描述性研究（回顾性研究评估数据）。
