Khamidov R I, Khalmuratova R A, Sattarova F K
Med Radiol (Mosk). 1987 Jul;32(7):7-9.
Aldosterone concentration and renin activity in the blood from the ulnar, inferior cava veins at the level of the 12th thoracic vertebra, the left and right renal veins were studied in 60 patients with arterial hypertension by means of a radioimmunoassay kit (France). The patients were divided into 4 groups: with primary and idiopathic hyperaldosteronism, renal-parenchymatous and essential arterial hypertension. A significant increase in aldosterone concentration in the blood from the ulnar vein was detected in all the groups, especially in primary and idiopathic hyperaldosteronism. Hyperaldosteronism in the patients with renal-parenchymatous and essential arterial hypertension was regarded as secondary in a stable and malignant course of arterial hypertension. The diagnosis of primary and idiopathic hyperaldosteronism was also confirmed by low blood renin activity. Renin activity in the peripheral venous blood was considerably elevated in renal-parenchymatous arterial hypertension and was within normal in essential hypertension. Aldosterone concentration in the blood from the vena cava inferior and renal veins was 1.6-2-fold as high on the affected side as on the contralateral one.
采用法国放射免疫分析试剂盒，对60例动脉高血压患者尺静脉、第12胸椎水平下腔静脉、左右肾静脉血中的醛固酮浓度和肾素活性进行了研究。患者分为4组：原发性和特发性醛固酮增多症、肾实质性和原发性动脉高血压组。所有组均检测到尺静脉血中醛固酮浓度显著升高，尤其是原发性和特发性醛固酮增多症组。肾实质性和原发性动脉高血压患者的醛固酮增多症在动脉高血压的稳定和恶性病程中被视为继发性。原发性和特发性醛固酮增多症的诊断也通过低血肾素活性得到证实。肾实质性动脉高血压患者外周静脉血中的肾素活性显著升高，原发性高血压患者的肾素活性在正常范围内。下腔静脉和肾静脉血中患侧的醛固酮浓度是对侧的1.6至2倍。
