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强脉冲光联合 KTP/PDL 样滤波器治疗面部毛细血管扩张的疗效和安全性。

Efficacy and Safety of Intense Pulsed Light With a KTP/PDLlike Filter for the Treatment of Facial Telangiectasias.

出版信息

J Drugs Dermatol. 2020 Sep 1;19(9):844-850. doi: 10.36849/JDD.2020.10.36849/JDD.2020.4834.

Abstract

BACKGROUND

An intense pulsed light (IPL) narrowband "KTP/PDL-like" filter (525–585 nm) may combine the tolerability of the IPL with the precision of KTP and PDL lasers. This study evaluated the impact of IPL with a KTP/PDL-like filter on telangiectasias.

METHODS

This was a single-center, prospective study of 17 subjects with facial telangiectasias and skin types I–III. Three monthly treatments were performed using this specific filter, with follow-up visits at 1, 3, and 6 months. Telangiectasia improvement was assessed by the investigator and subjects using a 5-point scale. Facial photographs and safety assessments were obtained at each visit. Subject discomfort was evaluated using a visual analog scale (VAS) immediately posttreatment, and subject downtime was recorded at each subsequent visit.

RESULTS

All facial telangiectasias significantly improved. At 1-month follow-up, >50% lesion clearance was noted in 97.1% of facial (n=36) and 85.7% of non-facial (n=7) lesions, with 73% of subjects satisfied or very satisfied. An increase in mean social downtime (0, 2.3, and 3 days) and VAS scores (3.5, 4.5, and 4.8) with treatments 1, 2, and 3, respectively, mirrored a stepwise increase in fluence with subsequent sessions.

CONCLUSIONS

The use of a novel IPL narrowband KTP/PDL-like filter can significantly improve facial and non-facial telangiectasias with minimal downtime. J Drugs Dermatol. 2020;19(9):844-850. doi:10.36849/JDD.2020.4834.

摘要

背景

强脉冲光(IPL)窄带“KTP/PDL 样”滤波器(525-585nm)可能结合 IPL 的耐受性与 KTP 和 PDL 激光的精确性。本研究评估了 IPL 与 KTP/PDL 样滤波器对毛细血管扩张症的影响。

方法

这是一项单中心、前瞻性研究,纳入了 17 名面部毛细血管扩张症和 I-III 型皮肤的受试者。使用这种特定的滤波器进行三次每月治疗,随访时间为 1、3 和 6 个月。毛细血管扩张症的改善由研究者和受试者使用 5 分制进行评估。每次就诊时均获得面部照片和安全性评估。治疗后即刻使用视觉模拟量表(VAS)评估受试者的不适程度,并在随后每次就诊时记录受试者的停机时间。

结果

所有面部毛细血管扩张症均显著改善。在 1 个月的随访时,97.1%(n=36)的面部和 85.7%(n=7)的非面部病变有>50%的病变清除,73%的受试者满意或非常满意。随着治疗的进行,平均社会停机时间(0、2.3 和 3 天)和 VAS 评分(3.5、4.5 和 4.8)逐渐增加,这反映了随后的治疗中能量密度的逐步增加。

结论

使用新型 IPL 窄带 KTP/PDL 样滤波器可显著改善面部和非面部毛细血管扩张症,同时停机时间最短。J 皮肤病药物治疗学杂志。2020;19(9):844-850. doi:10.36849/JDD.2020.4834.

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