Evidence and speculation: the response of confronted by autophagy in macrophages.

Bacteria of the genus cause diseases ranging from self-limited gastroenteritis to typhoid fever. Macrophages are immune cells that engulf and restrict . These cells will carry into the circulatory system and provoke a systemic infection. Therefore, the interaction between macrophages and intracellular is vital for its pathogenicity. As one of the immune responses of macrophages, autophagy, along with the fusion of autophagosomes with lysosomes, occupies an important position in eliminating . However, that can overcome cellular defensive responses and infect neighboring cells must derive strategies to escape autophagy. This review introduces novel findings on and macrophage autophagy as a mechanism against infection and explores the strategies used by to escape autophagy.