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急性外周性眩晕急诊就诊后受伤的风险:一项匹配队列研究。

Risk of injury after emergency department visit for acute peripheral vertigo: a matched-cohort study.

作者信息

Kim Hayoung, Lee Sihyoung, Kim Joonghee

机构信息

Department of Emergency Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

Department of Emergency Medicine, Sejong Hospital, Bucheon, Korea.

出版信息

Clin Exp Emerg Med. 2020 Sep;7(3):176-182. doi: 10.15441/ceem.19.064. Epub 2020 Sep 30.

Abstract

OBJECTIVE

Peripheral vertigo is one of the most common causes of the emergency department (ED) visits. It can impair balance and might predispose patients to injuries after discharge. The purpose of this study was to determine whether peripheral vertigo is associated with an increased risk of trauma.

METHODS

This matched-cohort study used the nationally representative dataset of de-identified claim information of 1 million randomly sampled individuals from a real Korean population, from 2002 to 2013. The exposure cohort included patients who visited EDs for new-onset peripheral vertigo without prior or concurrent injury. Each patient was randomly matched to five unexposed individuals (also without previous injury) by incidence density sampling. The primary outcome was a new injury within 1 year. The secondary outcomes were various injury subtypes. The time-dependent effect of the exposure was modeled using the extended Cox model. Age, sex, comorbidities, and household income level were included as covariates.

RESULTS

A total of 776 and 3,880 individuals were included as the exposure and comparison cohorts, respectively. The risks of trunk injury and upper extremity injury were significantly higher in the exposure cohort. Extended Cox models with multivariable adjustment showed significantly increased risk for up to 1 year, with the first 1-month; 1 month to 3 months; and 3 months to 1 year hazard ratios of 5.23 (95% confidence interval [CI], 2.83-9.64); 1.50 (95% CI, 1.02-2.20); and 1.37 (95% CI, 1.11-1.68), respectively.

CONCLUSION

Patients visiting EDs for acute peripheral vertigo are at a higher risk of a new injury for up to a year.

摘要

目的

外周性眩晕是急诊科就诊的最常见原因之一。它会损害平衡能力,并可能使患者在出院后易发生受伤情况。本研究的目的是确定外周性眩晕是否与创伤风险增加相关。

方法

这项匹配队列研究使用了2002年至2013年从韩国真实人群中随机抽取的100万匿名索赔信息的全国代表性数据集。暴露队列包括因新发外周性眩晕就诊于急诊科且无既往或并发损伤的患者。通过发病密度抽样,将每名患者与五名未暴露个体(也无既往损伤)进行随机匹配。主要结局是1年内发生的新损伤。次要结局是各种损伤亚型。使用扩展Cox模型对外周性眩晕暴露的时间依赖性效应进行建模。将年龄、性别、合并症和家庭收入水平作为协变量纳入分析。

结果

分别有776名和3880名个体被纳入暴露队列和对照队列。暴露队列中躯干损伤和上肢损伤的风险显著更高。经过多变量调整的扩展Cox模型显示,长达1年的风险显著增加,其中前1个月、1个月至3个月以及3个月至1年的风险比分别为5.23(95%置信区间[CI],2.83 - 9.64)、1.50(95%CI,1.02 - 2.20)和1.37(95%CI,1.11 - 1.68)。

结论

因急性外周性眩晕就诊于急诊科的患者在长达1年的时间内发生新损伤的风险更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c487/7550811/bd62b04ad206/ceem-19-064f1.jpg

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