Institute of Global Health, University Hospital Heidelberg , Heidelberg, Germany.
Centre de Recherche en Santé de Nouna , Nouna, Burkina Faso.
Glob Health Action. 2020 Dec 31;13(1):1829828. doi: 10.1080/16549716.2020.1829828.
The first line of malaria vector control to date mainly relies on the use of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS). For integrated vector management, targeting the vector larvae with biological larvicides such as () can be an effective additional mainstay. This study presents data from the second intervention year of a large-scale trial on biological larviciding with that was carried out in 127 rural villages and a semi-urban town in Burkina Faso. Here we present the reductions in malaria mosquitoes that were achieved by continuing the initial interventions for an additional year, important to assess sustainability and repeatability of the results from the first intervention year. Larviciding was performed applying two different larviciding choices ((a) treatment of all environmental breeding sites, and (b) selective treatment of those that were most productive for larvae indicated by remote sensing based risk maps). Adult spp. mosquito abundance was reduced by 77.4% (full treatment) and 63.5% (guided treatment) compared to the baseline year. The results showed that malaria vector abundance can be dramatically reduced using biological larviciding and that this effect can be achieved and maintained over several consecutive transmission seasons.
迄今为止，疟疾病媒控制的首要措施主要依赖于长效杀虫蚊帐（LLINs）和室内滞留喷洒（IRS）的使用。在综合病媒管理中，针对病媒幼虫使用生物杀幼虫剂（例如 ）可以作为一种有效的附加主要手段。本研究提供了在布基纳法索的 127 个农村村庄和一个半城市城镇进行的大规模生物杀幼虫试验的第二年干预数据。在此，我们展示了通过再进行一年初始干预来实现的疟疾蚊子数量减少，这对于评估第一年干预结果的可持续性和可重复性非常重要。通过应用两种不同的杀幼虫选择（(a) 处理所有环境滋生地，和 (b) 基于遥感的风险图指示的那些对 幼虫最具生产力的选择处理）进行了杀幼虫处理。与基线年相比， spp. 成蚊数量分别减少了 77.4%（全面处理）和 63.5%（有针对性处理）。结果表明，使用生物杀幼虫可以显著减少疟疾病媒的数量，并且这种效果可以在连续几个传播季节中实现和维持。
