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在 2019 冠状病毒病(COVID-19)大流行期间延长或重复使用一次性医用口罩和过滤式防颗粒物呼吸器:快速系统评价。

Extended use or reuse of single-use surgical masks and filtering face-piece respirators during the coronavirus disease 2019 (COVID-19) pandemic: A rapid systematic review.

机构信息

School of Allied Health, University of Limerick, Limerick, Ireland.

Evidence Synthesis Ireland, School of Nursing and Midwifery, National University of Ireland, Galway, Ireland.

出版信息

Infect Control Hosp Epidemiol. 2021 Jan;42(1):75-83. doi: 10.1017/ice.2020.1243. Epub 2020 Oct 8.

Abstract

BACKGROUND

Shortages of personal protective equipment during the coronavirus disease 2019 (COVID-19) pandemic have led to the extended use or reuse of single-use respirators and surgical masks by frontline healthcare workers. The evidence base underpinning such practices warrants examination.

OBJECTIVES

To synthesize current guidance and systematic review evidence on extended use, reuse, or reprocessing of single-use surgical masks or filtering face-piece respirators.

DATA SOURCES

We used the World Health Organization, the European Centre for Disease Prevention and Control, the US Centers for Disease Control and Prevention, and Public Health England websites to identify guidance. We used Medline, PubMed, Epistemonikos, Cochrane Database, and preprint servers for systematic reviews.

METHODS

Two reviewers conducted screening and data extraction. The quality of included systematic reviews was appraised using AMSTAR-2. Findings were narratively synthesized.

RESULTS

In total, 6 guidance documents were identified. Levels of detail and consistency across documents varied. They included 4 high-quality systematic reviews: 3 focused on reprocessing (decontamination) of N95 respirators and 1 focused on reprocessing of surgical masks. Vaporized hydrogen peroxide and ultraviolet germicidal irradiation were highlighted as the most promising reprocessing methods, but evidence on the relative efficacy and safety of different methods was limited. We found no well-established methods for reprocessing respirators at scale.

CONCLUSIONS

Evidence on the impact of extended use and reuse of surgical masks and respirators is limited, and gaps and inconsistencies exist in current guidance. Where extended use or reuse is being practiced, healthcare organizations should ensure that policies and systems are in place to ensure these practices are carried out safely and in line with available guidance.

摘要

背景

在 2019 年冠状病毒病(COVID-19)大流行期间,个人防护设备短缺,导致一线医护人员延长使用或重复使用一次性呼吸器和外科口罩。支持这些做法的证据基础值得研究。

目的

综合目前关于延长使用、重复使用或重新处理一次性外科口罩或过滤式面罩呼吸器的指南和系统评价证据。

资料来源

我们使用世界卫生组织、欧洲疾病预防控制中心、美国疾病控制与预防中心和英国公共卫生网站来确定指南。我们使用 Medline、PubMed、Epistemonikos、Cochrane 数据库和预印本服务器进行系统评价。

方法

两名审查员进行筛选和数据提取。使用 AMSTAR-2 评估纳入的系统评价质量。研究结果以叙述方式进行综合。

结果

共确定了 6 份指导文件。文件之间的详细程度和一致性存在差异。其中包括 4 项高质量的系统评价:3 项集中在 N95 呼吸器的再处理(消毒)上,1 项集中在外科口罩的再处理上。汽化过氧化氢和紫外线杀菌照射被认为是最有前途的再处理方法,但关于不同方法相对疗效和安全性的证据有限。我们没有发现大规模再处理呼吸器的成熟方法。

结论

关于延长使用和重复使用外科口罩和呼吸器的影响的证据有限,目前的指南存在差距和不一致。在实施延长使用或重复使用的情况下,医疗机构应确保制定政策和系统,以确保这些做法安全进行,并符合现有指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69f2/7588721/c61debe721c8/S0899823X2001243X_fig1.jpg

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