• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

白细胞红细胞增多症作为镰状细胞病患者细小病毒B19感染的一种罕见表现。

Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient.

作者信息

Patel Pratik A, Weinzierl Elizabeth P, Wechsler Daniel S

机构信息

Aflac Cancer & Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, USA.

Department of Pathology, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA, USA.

出版信息

Case Rep Pediatr. 2020 Sep 22;2020:8841607. doi: 10.1155/2020/8841607. eCollection 2020.

DOI:10.1155/2020/8841607
PMID:33029441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7528142/
Abstract

Parvovirus B19 infection in pediatrics most commonly causes fifth disease, a mild viral illness. Hematologic manifestations include severe anemia, especially in patients with chronic hemolytic anemias or who are immunocompromised. Because of the shortened life span of erythrocytes in patients with sickle cell disease, parvovirus infection can cause transient aplastic crisis which can be life-threatening. However, leukocytosis and thrombocytosis are rarely seen. We report leukoerythroblastosis as an unusual presentation of acute parvovirus B19 infection in a previously splenectomized 12-year-old boy with sickle cell disease.

摘要

小儿感染细小病毒B19最常见的是引起传染性红斑，这是一种轻度病毒性疾病。血液学表现包括严重贫血，尤其是在患有慢性溶血性贫血或免疫功能低下的患者中。由于镰状细胞病患者红细胞寿命缩短，细小病毒感染可导致短暂性再生障碍危象，这可能危及生命。然而，白细胞增多和血小板增多很少见。我们报告了一名12岁镰状细胞病患儿在脾切除术后出现红白血病，这是急性细小病毒B19感染的一种不寻常表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a37/7528142/56f1c916c075/CRIPE2020-8841607.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a37/7528142/56f1c916c075/CRIPE2020-8841607.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a37/7528142/56f1c916c075/CRIPE2020-8841607.001.jpg

相似文献

1
Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient.白细胞红细胞增多症作为镰状细胞病患者细小病毒B19感染的一种罕见表现。
Case Rep Pediatr. 2020 Sep 22;2020:8841607. doi: 10.1155/2020/8841607. eCollection 2020.
2
Transient aplastic crisis in patients with sickle cell disease. B19 parvovirus studies during a 7-year period.镰状细胞病患者的短暂再生障碍危象。7年期间的B19细小病毒研究。
Am J Dis Child. 1992 Nov;146(11):1328-30. doi: 10.1001/archpedi.1992.02160230086025.
3
Aplastic crisis associated with parvovirus B19 in an adult with hereditary spherocytosis.一名患有遗传性球形红细胞增多症的成年人中与细小病毒B19相关的再生障碍危象。
J Ark Med Soc. 1997 Sep;94(4):163-4.
4
Parvovirus B19 infection presenting with severe erythroid aplastic crisis during pregnancy in a woman with autoimmune hemolytic anemia and alpha-thalassemia trait: a case report.一名患有自身免疫性溶血性贫血和α地中海贫血特征的女性在孕期感染细小病毒B19并出现严重红系再生障碍危象：病例报告
J Med Case Rep. 2015 Mar 12;9:58. doi: 10.1186/s13256-015-0542-7.
5
Original Research: Parvovirus B19 infection in children with sickle cell disease in the hydroxyurea era.原创研究：羟基脲时代镰状细胞病患儿的细小病毒B19感染
Exp Biol Med (Maywood). 2016 Apr;241(7):749-54. doi: 10.1177/1535370216636723. Epub 2016 Mar 2.
6
Premature labor and leukoerythroblastosis in a newborn with parvovirus B19 infection.一名感染细小病毒B19的新生儿出现早产和类白血病反应。
Haematologica. 2005 Nov;90 Suppl:ECR38.
7
Sickle cell acute chest syndrome associated with parvovirus B19 infection: case series and review.与细小病毒B19感染相关的镰状细胞急性胸综合征：病例系列及综述
Am J Hematol. 1996 Mar;51(3):207-13. doi: 10.1002/(SICI)1096-8652(199603)51:3<207::AID-AJH5>3.0.CO;2-0.
8
Transient leukoerythroblastosis in a very low birth weight infant with parvovirus B19 infection.巨细胞病毒 B19 感染致极低出生体重儿一过性白细胞红细胞幼红细胞增多症。
Int J Infect Dis. 2009 Nov;13(6):e473-5. doi: 10.1016/j.ijid.2009.01.002. Epub 2009 Mar 23.
9
Severe aplastic anemia associated with human parvovirus B19 infection in a patient without underlying disease.一名无基础疾病患者发生与人类细小病毒B19感染相关的严重再生障碍性贫血。
Ann Hematol. 1999 Feb;78(2):83-6. doi: 10.1007/s002770050477.
10
Life-threatening anaemia caused by B19 parvovirus infection in a non-immunocompromised patient.一名非免疫功能低下患者因B19细小病毒感染导致危及生命的贫血。
Neth J Med. 1997 Feb;50(2):81-4. doi: 10.1016/s0300-2977(96)00076-9.

引用本文的文献

1
Leukoerythroblastosis in a Sickle Cell Patient With Pregnancy: An Interesting Peripheral Blood Smear Finding.一名镰状细胞病孕妇的类白血病反应：一项有趣的外周血涂片检查结果
J Hematol. 2022 Feb;11(1):15-20. doi: 10.14740/jh921. Epub 2021 Dec 13.

本文引用的文献

1
Viral Infections in Juvenile Myelomonocytic Leukemia: Prevalence and Clinical Implications.青少年骨髓单核细胞白血病中的病毒感染：患病率及临床意义
J Pediatr Hematol Oncol. 2004 Oct;26(10):636-641. doi: 10.1097/01.mph.0000140653.50344.5c.
2
A review of blood diseases and cytopenias associated with human parvovirus B19 infection.人类细小病毒 B19 感染相关血液疾病和细胞减少症的综述。
Rev Med Virol. 2015 Jul;25(4):224-40. doi: 10.1002/rmv.1839. Epub 2015 May 11.
3
Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management.
超越镰状细胞病表型并发症的定义：管理更新
ScientificWorldJournal. 2012;2012:949535. doi: 10.1100/2012/949535. Epub 2012 Aug 1.
4
Parvovirus B19 infection mimicking juvenile myelomonocytic leukemia.微小病毒B19感染酷似青少年型骨髓单核细胞白血病。
Int J Infect Dis. 2010 Sep;14 Suppl 3:e379-80. doi: 10.1016/j.ijid.2010.04.004. Epub 2010 Jul 6.
5
Definitions of the phenotypic manifestations of sickle cell disease.镰状细胞病表型表现的定义。
Am J Hematol. 2010 Jan;85(1):6-13. doi: 10.1002/ajh.21550.
6
Transient leukoerythroblastosis in a very low birth weight infant with parvovirus B19 infection.巨细胞病毒 B19 感染致极低出生体重儿一过性白细胞红细胞幼红细胞增多症。
Int J Infect Dis. 2009 Nov;13(6):e473-5. doi: 10.1016/j.ijid.2009.01.002. Epub 2009 Mar 23.
7
Transient myeloproliferation mimicking JMML associated with parvovirus infection of infancy.与婴儿细小病毒感染相关的类似幼年型粒单核细胞白血病的短暂性骨髓增殖症。
Pediatr Blood Cancer. 2009 Mar;52(3):411-3. doi: 10.1002/pbc.21842.
8
Parvovirus B19 infection in children with acute lymphoblastic leukemia is associated with cytopenia resulting in prolonged interruptions of chemotherapy.急性淋巴细胞白血病患儿感染细小病毒B19与血细胞减少有关，可导致化疗长期中断。
Clin Infect Dis. 2008 Feb 15;46(4):528-36. doi: 10.1086/526522.
9
Extreme leucocytosis: not always leukaemia.极度白细胞增多症：并非总是白血病。
Neth J Med. 2007 Jul-Aug;65(7):248-51.
10
Clinical presentations of parvovirus B19 infection.细小病毒B19感染的临床表现。
Am Fam Physician. 2007 Feb 1;75(3):373-6.