Kim Hyeyun, Kim Dong Wook, Lee Soon Tae, Byun Jung Ick, Seo Jong Geun, No Young Joo, Kang Kyung Wook, Kim Daeyoung, Kim Keun Tae, Cho Yong Won, Yang Kwang Ik
Department of Neurology, Catholic Kwandong University College of Medicine, International St. Mary's Hospital, Incheon, Korea.
Department of Neurology, Konkuk University School of Medicine, Seoul, Korea.
J Clin Neurol. 2020 Oct;16(4):547-555. doi: 10.3988/jcn.2020.16.4.547.
Epilepsy is a common neurological disorder that is mainly treated using antiepileptic drugs. Several antiepileptic drugs such as phenobarbital, phenytoin, primidone, and ethosuximide were developed in the early 20th century. More than 10 types of antiepileptic drugs have been developed since the 1990s, and there are now more than 20 antiepileptic drugs in active clinical use. The choice of antiepileptic drugs is based on the clinical features of the seizure types, electroencephalogram findings, epileptic syndrome, and drug stability. Currently there are 19 antiepileptic drugs approved by the Korean Food and Drug Administration, 18 of which (with the exclusion of brivaracetam) are covered by the National Health Insurance Service in Korea. We reviewed the selection of antiepileptic drugs according to the classification of epileptic seizures.
癫痫是一种常见的神经系统疾病，主要使用抗癫痫药物进行治疗。20世纪初开发了几种抗癫痫药物，如苯巴比妥、苯妥英、扑米酮和乙琥胺。自20世纪90年代以来，已开发出10多种抗癫痫药物，目前有20多种抗癫痫药物正在临床积极使用。抗癫痫药物的选择基于癫痫发作类型的临床特征、脑电图结果、癫痫综合征和药物稳定性。目前，韩国食品药品管理局批准了19种抗癫痫药物，其中18种（不包括布瓦西坦）在韩国由国民健康保险服务覆盖。我们根据癫痫发作的分类对抗癫痫药物的选择进行了综述。
