脊髓内间充质软骨肉瘤：基于文献综述对积极局部切除和辅助治疗的论证
Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature.
作者信息
Gopakumar Sricharan, Steele William J, Muir Matthew, Bhogani Zain, Britz Gavin
机构信息
Department of Neurosurgery, Baylor College of Medicine, One Baylor Plaza, United States.
Department of Neurosurgery, Houston Methodist Hospital Neurological Institute, Houston, TX, United States.
出版信息
Surg Neurol Int. 2020 May 2;11:95. doi: 10.25259/SNI_130_2020. eCollection 2020.
BACKGROUND
Mesenchymal chondrosarcoma is a rare cartilaginous neoplasm that typically involves the axial skeleton. Despite a well-circumscribed appearance, this tumor has a tendency to recur both locally and with distant metastases.
CASE DESCRIPTION
A 17-year-old patient presented with numbness and paresthesias in the lower extremities attributed to a T10-T11 intradural extramedullary mesenchymal chondrosarcoma. The patient was treated with aggressive local resection and adjuvant therapy. Here, this case and present literature are appropriately reviewed.
CONCLUSION
Although uncommon, intraspinal mesenchymal chondrosarcomas warrant both radical local resection and aggressive adjuvant therapy with chemoradiation to provide the greatest chance of progression-free survival.
背景
间叶性软骨肉瘤是一种罕见的软骨肿瘤，通常累及中轴骨骼。尽管其外观边界清晰，但该肿瘤有局部复发和远处转移的倾向。
病例描述
一名17岁患者因T10 - T11节段硬膜内髓外间叶性软骨肉瘤出现下肢麻木和感觉异常。患者接受了积极的局部切除和辅助治疗。在此，对该病例及现有文献进行了适当回顾。
结论
尽管罕见，但脊髓内间叶性软骨肉瘤需要进行根治性局部切除和积极的放化疗辅助治疗，以提供无进展生存的最大机会。
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