Department of Radiology, The Royal National Orthopaedic Hospital NHS Trust, Brockley Hill, Stanmore, Middlesex, HA7 4LP, UK.
Skeletal Radiol. 2013 May;42(5):611-26. doi: 10.1007/s00256-012-1521-3. Epub 2012 Oct 4.
Chondrosarcoma is the third most common primary malignant bone tumour. There are various histological subtypes of chondrosarcomas, of which conventional intramedullary chondrosarcoma is by far the most common. Rarer sub-types include clear cell chondrosarcoma, myxoid chondrosarcoma, mesenchymal chondrosarcoma and dedifferentiated chondrosarcoma. Chondrosarcoma is also classified into central, peripheral and periosteal, dependent upon the lesion site, and into primary chondrosarcoma if the lesion arises de novo and secondary chondrosarcoma if the tumour arises in a pre-existing lesion. The various subtypes of chondrosarcoma have characteristic imaging features that may aid diagnosis and may guide biopsy, therefore potentially preventing misdiagnosis. The aim of this article is to provide an overview of the pertinent clinical and imaging findings of the different forms of chondrosarcoma.
软骨肉瘤是第三大常见的原发性恶性骨肿瘤。软骨肉瘤有多种组织学亚型,其中最常见的是传统的髓内软骨肉瘤。较罕见的亚型包括透明细胞软骨肉瘤、黏液样软骨肉瘤、间叶性软骨肉瘤和去分化软骨肉瘤。软骨肉瘤还根据病变部位分为中央型、周围型和骨膜型,以及如果病变是原发性的则为原发性软骨肉瘤,如果肿瘤是在先前存在的病变中发生的则为继发性软骨肉瘤。软骨肉瘤的各种亚型具有特征性的影像学特征,这可能有助于诊断,并可能指导活检,从而潜在地避免误诊。本文的目的是提供不同类型软骨肉瘤的相关临床和影像学表现的概述。