Grupo de Bacterias y Cáncer, Universidad de Antioquia, Medellín, Colombia.
Grupo de Infección y Cáncer, Universidad de Antioquia, Medellín, Colombia.
Biomedica. 2020 Sep 1;40(3):534-545. doi: 10.7705/biomedica.5225.
Introduction: The sexually transmitted infection caused by Chlamydia trachomatis is the most common of bacterial etiology in the world. Although it can be asymptomatic in most cases, it can produce several reproductive health problems in women such as cervicitis, endometritis, and salpingitis. Despite its importance, the epidemiological data on this infection is insufficient in Medellín. Objective: To determine the prevalence of C. trachomatis in women from Medellín, identify possible risk factors, and evaluate its relationship with the human papillomavirus infection (HPV). Materials and methods: We conducted a multicenter cross-sectional study to detect C. trachomatis infection in 1,282 women using PCR and the LightMix 480 HT CT/NG™ commercial kit (Roche, Basel, Switzerland). Results: The total prevalence of C. trachomatis infection was 4.1% (95% CI: 2.9-5.3). We found an association between the presence of the infection and age, cigarette consumption, and the use of hormonalcontraceptives. Conclusion: The prevalence of the infection is similar to that reported in other parts of the world with young women being the most affected population. No relation was found with the presence of HPV.
沙眼衣原体引起的性传播感染是世界上最常见的细菌性病因。尽管在大多数情况下它可能无症状，但它会在女性中引起多种生殖健康问题，如宫颈炎、子宫内膜炎和输卵管炎。尽管其重要性，但在麦德林，关于这种感染的流行病学数据仍然不足。目的：确定来自麦德林的女性中沙眼衣原体的流行率，确定可能的危险因素，并评估其与人类乳头瘤病毒（HPV）感染的关系。材料和方法：我们进行了一项多中心横断面研究，使用 PCR 和 Roche（巴塞尔，瑞士）的 LightMix 480 HT CT/NG™商业试剂盒检测了 1282 名女性的沙眼衣原体感染。结果：沙眼衣原体感染的总流行率为 4.1%（95%CI：2.9-5.3）。我们发现感染的存在与年龄、吸烟和激素避孕药的使用有关。结论：感染的流行率与世界其他地区报告的相似，受影响的主要是年轻女性。与 HPV 的存在没有关系。
