Cardona-Arias Jaiberth Antonio, Gallego-Atehortúa Luz Helena, Ríos-Osorio Leonardo Alberto
Escuela de Microbiología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Área Asistencia, Dinámica IPS, Medellín, Colombia.
Rev Chilena Infectol. 2016 Oct;33(5):513-518. doi: 10.4067/S0716-10182016000500004.
Chlamydia trachomatis presents clinical consequences and it is barely studied in Colombia.
To compare the C. trachomatis infection in Bogotá and Medellín with specific frequencies by gender and age group, between 2012-2015.
Descriptive study of multiple groups, with 1,660 people in Bogotá and 1,087 in Medellin. Anti-Chlamydia trachomatis test with recombinant antigens MOMP, TARP and CPAF was applied; 100% sensitivity and 99.6% specificity. It was estimated and compared the frequency of infection by gender and age group, by hypothesis testing, confidence intervals and prevalence ratios.
The largest proportion were women and people between 30-39 years. The frequency of positive IgG in Bogotá was 15.6% (95% CI = 13.4 to 17.8) in Medellin 16.9% (95% CI = 13.4 to 20.4), while the frequency of positive IgM was 0% in Medellin and 0.2% (95% CI = 0.01-1.0) in Bogotá; it was higher in women. In Bogotá, the frequency was higher in younger than 30 years and lower in older than 50.
The high frequency of infection, its greater occurrence in women, the differences found in the age groups, the low number of investigations in Colombia and clinical risks associated with C. trachomatis, show the need to improve surveillance, screening and research in this infection.
沙眼衣原体可导致临床后果，而在哥伦比亚对其研究甚少。
比较2012年至2015年期间波哥大和麦德林沙眼衣原体感染情况，按性别和年龄组列出具体感染率。
多组描述性研究，波哥大有1660人，麦德林有1087人。采用含重组抗原MOMP、TARP和CPAF的抗沙眼衣原体检测；灵敏度为100%，特异性为99.6%。通过假设检验、置信区间和患病率比估算并比较按性别和年龄组划分的感染率。
女性以及30至39岁人群占比最大。波哥大IgG阳性率为15.6%（95%置信区间=13.4%至17.8%），麦德林为16.9%（95%置信区间=13.4%至20.4%），而麦德林IgM阳性率为0%，波哥大为0.2%（95%置信区间=0.01%-1.0%）；女性感染率更高。在波哥大，30岁以下人群感染率较高，50岁以上人群感染率较低。
感染率高、在女性中更易发生、各年龄组存在差异、哥伦比亚相关调查数量少以及沙眼衣原体相关临床风险，表明有必要加强对该感染的监测、筛查和研究。
