Taborsky Barbara, English Sinead, Fawcett Tim W, Kuijper Bram, Leimar Olof, McNamara John M, Ruuskanen Suvi, Sandi Carmen
Behavioural Ecology Division, Institute of Ecology and Evolution, University of Bern, Bern, Switzerland.
School of Biological Sciences, University of Bristol, Bristol, UK.
Trends Ecol Evol. 2021 Jan;36(1):39-48. doi: 10.1016/j.tree.2020.09.003. Epub 2020 Oct 5.
All organisms have a stress response system to cope with environmental threats, yet its precise form varies hugely within and across individuals, populations, and species. While the physiological mechanisms are increasingly understood, how stress responses have evolved remains elusive. Here, we show that important insights can be gained from models that incorporate physiological mechanisms within an evolutionary optimality analysis (the 'evo-mecho' approach). Our approach reveals environmental predictability and physiological constraints as key factors shaping stress response evolution, generating testable predictions about variation across species and contexts. We call for an integrated research programme combining theory, experimental evolution, and comparative analysis to advance scientific understanding of how this core physiological system has evolved.
所有生物体都有一个应激反应系统来应对环境威胁，然而其确切形式在个体、种群和物种内部及之间差异巨大。虽然生理机制越来越为人所知，但应激反应是如何进化的仍然难以捉摸。在这里，我们表明，通过在进化最优性分析（“进化 - 生理机制”方法）中纳入生理机制的模型可以获得重要见解。我们的方法揭示了环境可预测性和生理限制是塑造应激反应进化的关键因素，从而产生了关于物种间和不同环境下变异的可测试预测。我们呼吁开展一个综合研究项目，将理论、实验进化和比较分析结合起来，以推进对这个核心生理系统如何进化的科学理解。
