Kenny Jon-Émile S, Barjaktarevic Igor, Eibl Andrew M, Parrotta Matthew, Long Bradley F, Eibl Joseph K
Health Sciences North Research Institute Sudbury Ontario Canada.
Division of Pulmonary and Critical Care, Department of Medicine David Geffen School of Medicine at UCLA Los Angeles California.
Health Sci Rep. 2020 Oct 5;3(4):e190. doi: 10.1002/hsr2.190. eCollection 2020 Dec.
To test the feasibility of a novel, wearable carotid Doppler ultrasound to track changes in cardiac output induced by end-inspiratory and end-expiratory occlusion tests.
We observed the pattern of Doppler change of the common carotid artery during a simulated end-inspiratory and expiratory occlusion test (sEIOT/sEEOT) in 10, nonventilated, healthy subjects. Simultaneously, we measured the Doppler signal of the descending aorta using duplex ultrasound (Xario, Toshiba Medical Systems) and stroke volume (SV) using noninvasive pulse contour analysis (Clearsight, Edwards Lifesciences, Irvine, California).
During sEIOT, SV, maximum velocity time integral (VTI) of the descending aorta, and common carotid fell by 25.7% ( = .0131), 26.1% ( < .0001), and 18.5% ( < .0001), respectively. During sEEOT, SV, maximum VTI of the descending aorta, and common carotid rose by: 41.3% ( = .0051), 28.3% ( < .0001), and 41.6% ( < .0001), respectively. There was good correlation between change in aortic VTI and carotid VTI ( = 0.79); SV and aortic VTI ( = 0.82), and SV and carotid VTI ( = 0.95).The coefficient of variation of the VTI measured by the Doppler patch was roughly 60% less than that of the duplex system.
The pattern of SV change induced by a sEIOT/sEEOT in nonmechanically ventilated volunteers is reflected in the common carotid artery and descending aorta. The VTI variability of the Doppler patch was less than that of the traditional, duplex Doppler.
测试一种新型可穿戴式颈动脉多普勒超声追踪吸气末和呼气末闭塞试验引起的心输出量变化的可行性。
我们在10名未通气的健康受试者中观察了模拟吸气末和呼气末闭塞试验（sEIOT/sEEOT）期间颈总动脉的多普勒变化模式。同时，我们使用双功超声（Xario，东芝医疗系统）测量降主动脉的多普勒信号，并使用无创脉搏轮廓分析（Clearsight，爱德华兹生命科学公司，加利福尼亚州欧文）测量每搏输出量（SV）。
在sEIOT期间，SV、降主动脉的最大速度时间积分（VTI）和颈总动脉分别下降了25.7%（P = 0.0131）、26.1%（P < 0.0001）和18.5%（P < 0.0001）。在sEEOT期间，SV、降主动脉的最大VTI和颈总动脉分别上升了：41.3%（P = 0.0051）、28.3%（P < 0.0001）和41.6%（P < 0.0001）。主动脉VTI变化与颈动脉VTI之间存在良好相关性（r = 0.79）；SV与主动脉VTI（r = 0.82），以及SV与颈动脉VTI（r = 0.95）。多普勒贴片测量的VTI变异系数比双功系统的变异系数大约低60%。
sEIOT/sEEOT在非机械通气志愿者中引起的SV变化模式反映在颈总动脉和降主动脉中。多普勒贴片的VTI变异性小于传统双功多普勒。
