Solaru Samantha, Alluri Ram K, Wang Jeffrey C, Hah Raymond J
5116University of Southern California, Los Angeles, CA, USA.
yKeck School of Medicine of the University of Southern California, Orthopaedic Surgery, CA, USA.
Global Spine J. 2021 Sep;11(7):1148-1155. doi: 10.1177/2192568220962439. Epub 2020 Oct 9.
Review.
Venothromboembolic (VTE) complications, composed of deep vein thrombosis and pulmonary embolism are commonly observed in the perioperative setting. There are approximately 500 000 postoperative VTE cases annually in the United States and orthopedic procedures contribute significantly to this incidence. Data on the use of VTE prophylaxis in elective spinal surgery is sparse. This review aims to provide an updated consensus within the literature defining the risk factors, diagnosis, and the safety profile of routine use of pharmacological prophylaxis for VTE in elective spine surgery patients.
A comprehensive review of the literature and compilation of findings relating to current identified risk factors for VTE, diagnostic methods, and prophylactic intervention and safety in elective spine surgery.
VTE prophylaxis use is still widely contested in elective spine surgery patients. The outlined benefits of mechanical prophylaxis compared with chemical prophylaxis varies among practitioners.
The benefits of any form of VTE prophylaxis continues to remain a controversial topic in the elective spine surgery setting. A specific set of guidelines for implementing prophylaxis is yet to be determined. As more risk factors for thromboembolic events are identified, the complexity surrounding intervention selection increases. The benefits of prophylaxis must also continue to be balanced against the increased risk of bleeding events and neurologic injury.
综述。
静脉血栓栓塞(VTE)并发症,包括深静脉血栓形成和肺栓塞,在围手术期很常见。在美国,每年约有50万例术后VTE病例,骨科手术在这一发病率中占很大比例。关于择期脊柱手术中VTE预防措施使用的数据很少。本综述旨在提供文献中的最新共识,以确定择期脊柱手术患者常规使用药物预防VTE的风险因素、诊断方法和安全性。
全面回顾文献,并汇总与当前已确定的择期脊柱手术中VTE风险因素、诊断方法以及预防性干预和安全性相关的研究结果。
在择期脊柱手术患者中,VTE预防措施的使用仍存在广泛争议。与化学预防相比,机械预防的既定益处因从业者而异。
在择期脊柱手术中,任何形式的VTE预防措施的益处仍然是一个有争议的话题。尚未确定实施预防措施的具体指南。随着更多血栓栓塞事件风险因素的确定,干预选择的复杂性增加。预防措施的益处还必须继续与出血事件和神经损伤风险的增加相权衡。