Research Laboratory Education, Motricité, Sport et Santé, EM2S, LR19JS01, High Institute of Sport and Physical Education of Sfax, University of Sfax, Tunisia.
Research Laboratory Education, Motricité, Sport et Santé, EM2S, LR19JS01, High Institute of Sport and Physical Education of Sfax, University of Sfax, Tunisia.
Behav Brain Res. 2021 Jan 15;397:112956. doi: 10.1016/j.bbr.2020.112956. Epub 2020 Oct 7.
Middle-aged women display many physiological and cognitive alterations resulting from aging and physical inactivity as well as other changes that occur as a function of menopause. Caffeine consumption is highest in this age with women having a particular greater sensitivity to caffeine than men. Its effects on functional and cognitive functions are controversial and seem to depend on the dose intake. This study aimed to assess the effect of low (100mg) and high (400mg) doses of caffeine consumption on cognitive (simple reaction time) and functional (upper and low body muscle endurance, aerobic endurance and functional mobility) performances. These performances were evaluated in 19 healthy middle-aged women by the 30-Second Chair Stand test for lower body muscle endurance, the 30sec Arm Curl Test for upper body muscle endurance, the 2-Minute Step test for aerobic endurance, The Timed Up and Go test for functional mobility and the simple reaction time test for reaction time, 60min after a treatment capsule intake (100mg caffeine/400mg caffeine/placebo). Low caffeine consumption significantly improved (p<.005) cognitive performance, while high caffeine consumption did not. However, the functional performance significantly improved (p<.05) after high caffeine consumption but not after low caffeine consumption. Except, the functional mobility performance significantly improved (p<.05) after both low and high caffeine consumption with better improvement (p<.05) after the high dose. In conclusion, low caffeine consumption improved cognitive performance and high caffeine consumption improved functional performance but the functional mobility improved after both low and high caffeine consumption in middleaged women.
中年女性表现出许多与衰老和身体不活动以及其他与绝经相关的变化相关的生理和认知改变。在这个年龄段，女性的咖啡因摄入量最高，而且比男性对咖啡因的敏感性更高。其对功能和认知功能的影响存在争议，似乎取决于剂量摄入。本研究旨在评估低（100mg）和高（400mg）剂量咖啡因摄入对认知（简单反应时间）和功能（上下肢肌肉耐力、有氧耐力和功能机动性）表现的影响。通过 30 秒椅子站立测试评估下肢肌肉耐力，通过 30 秒手臂卷曲测试评估上肢肌肉耐力，通过 2 分钟踏步测试评估有氧耐力，通过计时起立行走测试评估功能机动性，通过简单反应时间测试评估反应时间，在治疗胶囊摄入后 60 分钟（100mg 咖啡因/400mg 咖啡因/安慰剂）评估 19 名健康中年女性的这些表现。低咖啡因摄入显著改善（p<.005）认知表现，而高咖啡因摄入则没有。然而，高咖啡因摄入后功能表现显著改善（p<.05），而低咖啡因摄入后则没有。除了功能机动性表现，低咖啡因和高咖啡因摄入后都显著改善（p<.05），高剂量后改善更明显（p<.05）。总之，低咖啡因摄入可改善认知表现，高咖啡因摄入可改善功能表现，但在中年女性中，低咖啡因和高咖啡因摄入后均可改善功能机动性。
