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全髋关节置换术后使用不含皮下缝合的辛酯-2-氰基丙烯酸酯组织粘合剂闭合伤口:一项对32例患者进行3个月随访对照的前瞻性观察研究。

Octyl-2-cyanoacrylate tissue adhesive without subcuticular suture for wound closure after total hip arthroplasty: a prospective observational study on thirty-two cases with controls for 3 months follow-up.

作者信息

Wang Li-Shen, Wang Xin-Yu, Tu Hao-Tian, Huang Yi-Fan, Qi Xin, Gao Yu-Hang

机构信息

Department of Orthopedic Surgery, The First Hospital of Jilin University, Changchun, Jilin, 130021, China.

出版信息

J Orthop Surg Res. 2020 Oct 10;15(1):467. doi: 10.1186/s13018-020-01997-9.

DOI:10.1186/s13018-020-01997-9
PMID:33036638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7547444/
Abstract

BACKGROUND

Whether using tissue adhesive alone after subcutaneous suture can close the skin incision with safety as well as cosmetic appearance after total hip arthroplasty was not clear.

METHODS

A prospective study was conducted. The same surgical methods were consistent throughout the entire study. After implanting prosthesis, the joint capsule was reconstructed. Fascial and subcutaneous layer were respectively closed by continuous running barbed suture. Patients were randomized allocated to group A with octyl-2-cyanoacrylate tissue adhesive alone, to group B with tissue adhesive after continuous subcuticular suture, or to group C with skin staples. Time of closure, drainage, pain, wound complications, and cosmesis were compared. All data were analyzed statistically.

RESULTS

There was no significant difference in drainage, Visual Analog Scale score or early wound complications between the three groups. However, there was significant difference in time of closure (P = 0.013). In pairwise comparison, time of closure in groups A and B was significantly longer than those in group C (P = 0.001 and P = 0.023, respectively); time of closure in group A was significantly shorter than those in group B (P = 0.003). Patient and Observer Scar Assessment Scale total scores were not significantly different at 6 weeks and 3 months postoperatively (P = 0.078 and P = 0.284, respectively).

CONCLUSION

Tissue adhesive without subcuticular suture was similar with a combination of subcuticular suture and tissue adhesive as well skin staples in terms of safety and cosmetic appearance after total hip arthroplasty.

摘要

背景

全髋关节置换术后仅使用组织粘合剂进行皮下缝合能否安全闭合皮肤切口并达到美观效果尚不清楚。

方法

进行一项前瞻性研究。在整个研究过程中,手术方法保持一致。植入假体后,重建关节囊。分别用连续倒刺缝线闭合筋膜层和皮下层。患者被随机分为三组:A组仅使用2-氰基丙烯酸辛酯组织粘合剂;B组在连续皮下缝合后使用组织粘合剂;C组使用皮肤吻合钉。比较三组的闭合时间、引流情况、疼痛程度、伤口并发症及美观度。所有数据进行统计学分析。

结果

三组在引流、视觉模拟评分或早期伤口并发症方面无显著差异。然而,在闭合时间上存在显著差异(P = 0.013)。两两比较显示,A组和B组的闭合时间显著长于C组(分别为P = 0.001和P = 0.023);A组的闭合时间显著短于B组(P = 0.003)。术后6周和3个月时,患者和观察者瘢痕评估量表总分无显著差异(分别为P = 0.078和P = 0.284)。

结论

全髋关节置换术后,不进行皮下缝合直接使用组织粘合剂在安全性和美观度方面与皮下缝合联合组织粘合剂以及皮肤吻合钉相似。

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