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有冠状动脉疾病的高出血风险患者。

The High Bleeding Risk Patient with Coronary Artery Disease.

机构信息

Department of Clinical and Experimental Medicine, Policlinico "G. Martino", University of Messina, Via C Valeria 1, Messina 98100, Italy; Interventional Cardiology Unit, Policlinico G. Martino, Via C Valeria 1, Messina 98100, Italy.

UGC del Corazón, Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga 29010, Spain.

出版信息

Cardiol Clin. 2020 Nov;38(4):481-490. doi: 10.1016/j.ccl.2020.06.002. Epub 2020 Sep 17.

DOI:10.1016/j.ccl.2020.06.002
PMID:33036711
Abstract

Out-of-hospital bleeding is a common complication after percutaneous coronary intervention (PCI) due to the concomitant need for dual antiplatelet therapy. A significant proportion of patients undergoing PCI carry specific clinical characteristics posing them at high bleeding risk (HBR), increasing the risk of hemorrhagic complications secondary to antithrombotic therapy. Identifying patients at HBR and adjust antithrombotic therapy accordingly to optimize treatment benefits and risk is a challenge of modern cardiology. Recently, multiple definitions and tools have been provided to help clinicians with prognostic stratification and treatment decision making in this subgroup.

摘要

院外出血是经皮冠状动脉介入治疗(PCI)后的常见并发症,这是由于需要同时进行双联抗血小板治疗。相当一部分接受 PCI 的患者具有特定的临床特征,使他们处于高出血风险(HBR),增加了抗血栓治疗继发出血并发症的风险。确定 HBR 患者并相应调整抗血栓治疗以优化治疗获益和风险是现代心脏病学的一项挑战。最近,已经提供了多种定义和工具来帮助临床医生对这一亚组进行预后分层和治疗决策。

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引用本文的文献

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Clinical Outcomes and Prognostic Factors in Complex, High-Risk Indicated Procedure (CHIP) and High-Bleeding-Risk (HBR) Patients Undergoing Percutaneous Coronary Intervention with Sirolimus-Eluting Stent Implantation: 4-Year Results.接受西罗莫司洗脱支架植入术的复杂、高危指征性手术(CHIP)及高出血风险(HBR)患者经皮冠状动脉介入治疗的临床结局及预后因素:4年结果
J Clin Med. 2023 Aug 15;12(16):5313. doi: 10.3390/jcm12165313.