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新型冠状病毒肺炎的潜在抑制剂和功能性食品成分作为 COVID-19 的营养补充剂:综述。

Potential Inhibitors for SARS-CoV-2 and Functional Food Components as Nutritional Supplement for COVID-19: A Review.

机构信息

ICAR - National Institute of High Security Animal Diseases, Bhopal, Madhya Pradesh, 462021, India.

Department of Biophysics, All India Institute of Medical Sciences, New Delhi, 110029, India.

出版信息

Plant Foods Hum Nutr. 2020 Dec;75(4):458-466. doi: 10.1007/s11130-020-00861-9. Epub 2020 Oct 10.

Abstract

The severe acute respiratory syndrome is a viral respiratory infection and commonly called as COVID-19, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It widely transmitted through direct or indirect contact. Currently, no specific treatment against SARS-CoV-2 are available; only prevention and supportive strategy are the preventive measures. The present review emphasizes the latest research related to COVID-19 and SARS-CoV-2 virus as well as the current status of potential inhibitors identified. Recent interest in SARS-CoV-2 has focused on transmission, symptoms, structure, and its structural proteins that exhibit promising therapeutics targets for rapid identification of potential inhibitors. The quick identification of potential inhibitors and immune-boosting functional food ingredients are crucial to combat this pandemic disease. We also tried to give an overview of the functional food components as a nutritional supplement, which helps in boosting our immune system and could be useful in preventing the COVID-19 and/or to improve the outcome during therapy.

摘要

严重急性呼吸系统综合症是一种病毒性呼吸道感染,通常称为 COVID-19,由严重急性呼吸系统综合症冠状病毒 2(SARS-CoV-2)引起。它通过直接或间接接触广泛传播。目前,尚无针对 SARS-CoV-2 的特定治疗方法;只有预防和支持策略是预防措施。本综述强调了与 COVID-19 和 SARS-CoV-2 病毒相关的最新研究以及已确定的潜在抑制剂的现状。最近人们对 SARS-CoV-2 的兴趣集中在传播、症状、结构及其结构蛋白上,这些蛋白为快速鉴定潜在抑制剂提供了有希望的治疗靶点。快速鉴定潜在抑制剂和免疫增强功能性食品成分对于对抗这一流行疾病至关重要。我们还试图概述功能性食品成分作为一种营养补充剂,它有助于增强我们的免疫系统,在预防 COVID-19 和/或改善治疗期间的结果方面可能有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e09/7546941/1369b38ad202/11130_2020_861_Fig1_HTML.jpg

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