Department of Urology, Ege University Hospital, Izmir 35100, Turkey.
Department of Radiology, Ege University Hospital, Izmir 35100, Turkey.
Urol J. 2020 Oct 4;18(4):417-421. doi: 10.22037/uj.v16i7.6025.
We aimed to investigate the histopathological correlation of the suspected prostate malignancy detected in multiparametric prostate magnetic resonance imaging (mpMRI).
The data of 93 patients underwent radical prostatectomy and had preoperative mpMRI were examined. Age and pre-operative Prostate-Specific Antigen value were retrospectively collected from patient files. The pathology specimens were examined again and post-operative ISUP grade group, other pathological findings (seminal vesicle invasion, lymph node involvement and extraprostatic extension), pre-operative mpMRI were re-examined and PIRADS score, extracapsular extension, seminal vesicle invasion, neurovascular bundle invasion, lymph node involvement and ADC values were recorded.
151 (92,07%) of 164 lesions detected in mpMRI were histopathologically correlated. 80% of patients with seminal vesicle invasion (P < 0.001), 28.8% of patients with extracapsular extension (P < 0.052) and 42.9% of patients with lymph node involvement (P = .001) in mpMRI were histopathologically correlated. A significant relationship was found between PIRADS scores and ISUP grade groups (P < 0.001). There was a negative correlation between ADC values and ISUP grade groups (P < 0.001).
Our study showed that the lesions detected by mpMRI showed a high histopathological correlation.
我们旨在研究多参数前列腺磁共振成像（mpMRI）检测到的疑似前列腺恶性肿瘤的组织病理学相关性。
对 93 例行根治性前列腺切除术且术前有 mpMRI 的患者的数据进行了检查。从患者档案中回顾性收集了年龄和术前前列腺特异性抗原值。再次检查病理标本，并检查术后 ISUP 分级组、其他病理发现（精囊侵犯、淋巴结受累和前列腺外侵犯）、术前 mpMRI 并记录 PIRADS 评分、包膜外侵犯、精囊侵犯、神经血管束侵犯、淋巴结受累和 ADC 值。
mpMRI 检测到的 164 个病灶中有 151 个（92.07%）与组织病理学相关。mpMRI 中 80%的精囊侵犯患者（P<0.001）、28.8%的包膜外侵犯患者（P<0.052）和 42.9%的淋巴结受累患者（P=0.001）与组织病理学相关。PIRADS 评分与 ISUP 分级组之间存在显著关系（P<0.001）。ADC 值与 ISUP 分级组之间呈负相关（P<0.001）。
我们的研究表明，mpMRI 检测到的病变具有较高的组织病理学相关性。
