感染鼠麻风杆菌的小鼠的黏附细胞对体外抗体反应的增强作用。
Enhancement of the antibody response in vitro by adherent cells from mice infected with Mycobacterium lepraemurium.
作者信息
Watson S R, Brown I N, Sljivić V S
出版信息
Infect Immun. 1977 Aug;17(2):263-7. doi: 10.1128/iai.17.2.263-267.1977.
Abstract
Spleen cells from mice systemically infected 4 to 6 weeks previously with Mycobacterium lepraemurium gave an enhanced primary antibody response in vitro to sheep erythrocytes, but responded normally to dinitrophenylated polyumerized flagellin. The ability to enhance the response was associated with the glass-adherent spleen cell population and with peritoneal cells. Similar cells obtained from infected mice depleted of T lymphocytes failed to enhance the antibody response. These studies suggest that macrophages that became activated during the development of cell-mediated immunity to infection can also stimulate antibody responses to thymus-dependent antigens.
摘要
4至6周前全身感染鼠麻风杆菌的小鼠脾脏细胞，在体外对绵羊红细胞产生增强的初次抗体反应，但对二硝基苯基化聚合鞭毛蛋白反应正常。增强反应的能力与玻璃黏附性脾脏细胞群体及腹腔细胞有关。从感染小鼠中获得的、T淋巴细胞已耗尽的类似细胞无法增强抗体反应。这些研究表明，在针对感染的细胞介导免疫发展过程中被激活的巨噬细胞，也能刺激对胸腺依赖性抗原的抗体反应。
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2
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Immunology. 1968 Apr;14(4):599-600.
3
Induction of immunity and tolerance in vitro in the absence of phagocytic cells.在无吞噬细胞的情况下体外诱导免疫和耐受。
Nature. 1970 Feb 21;225(5234):731-2. doi: 10.1038/225731a0.
4
Potentiation of the T-lymphocyte response to mitogens. II. The cellular source of potentiating mediator(s).T淋巴细胞对丝裂原反应的增强作用。II. 增强介质的细胞来源。
J Exp Med. 1972 Jul 1;136(1):143-55. doi: 10.1084/jem.136.1.143.
5
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6
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7
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