Dirección de Administración y Desarrollo de Personal, Instituto de Seguridad Social del Estado de México y Municipios (ISSEMyM), Toluca, Mexico.
Pediatr Obes. 2021 May;16(5):e12740. doi: 10.1111/ijpo.12740. Epub 2020 Oct 11.
Some comorbidities are risk factors for severe coronavirus disease (Covid-19) but it is unknown whether some increase susceptibility to Covid-19 in children. In this Mexican case-control study, contact with patients with Covid-19, or having obesity, or having diabetes, or hypertension or been immunosuppressed independently increased the risk for Covid-19 in the whole sample analysis. However, only contact history and obesity remained statistically significant in the separated analysis of girls and boys. The results suggest that obesity is not only associated with severe disease but also increases risk for Covid-19. Contrary to findings in adults, no difference between cases and controls was found for gender, presence of pneumonia or surrogates of severe disease including admission to intensive care unit, tracheal intubation or whether patient had died. This indicates that Covid-19 is less severe in children than adults. Future research is needed to establish the mechanisms involved in obesity and Covid-19 in children.
一些合并症是严重冠状病毒病（Covid-19）的危险因素，但尚不清楚某些因素是否会使儿童更容易感染 Covid-19。在这项墨西哥病例对照研究中，与 Covid-19 患者接触，或肥胖、糖尿病、高血压或免疫抑制，独立增加了全样本分析中 Covid-19 的风险。然而，在对女孩和男孩的单独分析中，只有接触史和肥胖仍然具有统计学意义。研究结果表明，肥胖不仅与严重疾病有关，而且还会增加感染 Covid-19 的风险。与成年人的研究结果相反，在病例和对照组之间，性别、肺炎的存在或严重疾病的替代指标（包括入住重症监护病房、气管插管或患者是否死亡）没有差异。这表明 Covid-19 在儿童中比在成年人中要轻。需要进一步研究以确定肥胖和儿童 Covid-19 之间的相关机制。
