Douard H, Sermon F, Mora B, Broustet J P
Ann Cardiol Angeiol (Paris). 1987 Jun;36(6):319-24.
The anti-ischemic activity of Verapamil (360 mg/24 h) is compared with a cardioselective betablocker, Atenolol (100 mg/24 h), in a single blind study with computerized stress tests. Although acting through different mechanisms, and are evaluated indirectly by measurements with equal cardiac work and frequency, the improvement of the performance, the decrease of the sub-denivellation at the end of the stress and the frequency of interruption because of pain, seem approximately similar for both medications.
在一项采用计算机化应激测试的单盲研究中，将维拉帕米（360毫克/24小时）的抗缺血活性与一种心脏选择性β受体阻滞剂阿替洛尔（100毫克/24小时）进行了比较。尽管二者作用机制不同，且通过同等心脏做功和心率测量进行间接评估，但两种药物在改善运动表现、降低应激结束时的亚极量水平以及因疼痛导致的中断频率方面，效果似乎大致相似。
