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普萘洛尔和阿替洛尔对劳力性心绞痛患者的抗心绞痛及血流动力学作用

[Antianginal and hemodynamic effect of propranolol and atenolol in patients with exertion angina].

作者信息

Desiatnichenko V M

出版信息

Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1984;7(2):71-5.

PMID:6508931
Abstract

In patients with angina of effort, the changes of the central hemodynamic indices were estimated after oral administration of effective antianginal doses of propranolol and the cardioselective beta-blocker atenolol, which had been individually selected. Atenolol maximum effects on the hemodynamics were somewhat superior to those of propranolol. At the same time, the degree of hemodynamic changes did not correlate with their antianginal action. The effect of atenolol on the total peripheral vascular resistance was not higher as compared to that of propranolol.

摘要

在劳力性心绞痛患者中,口服经个体化选择的有效抗心绞痛剂量的普萘洛尔和心脏选择性β受体阻滞剂阿替洛尔后,评估其中心血流动力学指标的变化。阿替洛尔对血流动力学的最大作用在一定程度上优于普萘洛尔。同时,血流动力学变化程度与其抗心绞痛作用不相关。与普萘洛尔相比,阿替洛尔对总外周血管阻力的作用并不更强。

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[Atenolol in the treatment of angina pectoris].阿替洛尔治疗心绞痛
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