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[血液微循环形态学基础的研究成果与展望]

[Results and prospects for the study of the morphologic basis of microcirculation of the blood].

作者信息

Kozlov V I, Kulikov V V, Tikhomirov A N

出版信息

Arkh Anat Gistol Embriol. 1987 May;92(5):5-19.

PMID:3304221
Abstract

The survey of the works, performed during the 11th five-year period in studying general biological regularities of microcirculation, demonstrates certain success in investigations developed in the following directions: functional geometry of the hemo-microcirculatory bed; elaboration of quantitative and qualitative analysis methods of the microcirculatory system elements; functional morphology of the vascular endothelium; experimental analysis of adaptive mechanisms of the microcirculatory bed; clinical-morphological investigations of microcirculation. Formation of structural-functional units, ensuring specialization of microcirculation in organs, forms the base of the functional geometry of the microcirculatory bed. This makes necessary conditions for compartmentalization of some micro-region in an organ and spatial distribution of various liquid media in dependence of certain topology of microvessels. The most perspective ways in development of morphological investigations, concerning the general biological regularities of microcirculation, are discussed.

摘要

在“十一五”期间开展的关于微循环一般生物学规律研究的工作调查表明,在以下几个方向开展的研究取得了一定成果:血液微循环床的功能几何学;微循环系统元件定量和定性分析方法的完善;血管内皮的功能形态学;微循环床适应性机制的实验分析;微循环的临床形态学研究。确保器官微循环特化的结构功能单元的形成,构成了微循环床功能几何学的基础。这为器官中某些微区域的分隔以及各种液体介质根据微血管的特定拓扑结构进行空间分布创造了必要条件。文中还讨论了关于微循环一般生物学规律的形态学研究发展中最具前景的方法。

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