Bobrik I I, Shevchenko E A, Cherkasov V G, Morin M V, Parakhin A I
Arkh Anat Gistol Embriol. 1986 Jun;90(6):9-13.
By means of transmissive electron microscopy methods, general regularities in development of the microcirculatory system have been studied at early stages of the human prenatal ontogenesis in functionally different organs. Ultrastructure of two cell types has been described in the mesenchyme of human embryos. Formation mechanisms of the primary blood vessels belonging to the protocapillary type are revealed. Structural peculiarities of the primary protocapillary network differentiating into various links of the secondary organospecific hemomicrocirculatory bed are distinguished. Certain stageness in development of the microcirculatory system is stated, its blood circulatory compartment including. Two stages are determined in development of the microcirculatory system: prevascular and vascular microcirculation. The latter includes the precirculatory and circulatory phases.
借助透射电子显微镜方法，在人类产前个体发育的早期阶段，对功能不同器官的微循环系统发育的一般规律进行了研究。已描述了人类胚胎间充质中两种细胞类型的超微结构。揭示了属于原毛细血管类型的初级血管的形成机制。区分了分化为次级器官特异性血液微循环床各个环节的初级原毛细血管网络的结构特点。指出了微循环系统发育中的某些阶段性，包括其血液循环部分。确定了微循环系统发育的两个阶段：血管前微循环和血管微循环。后者包括循环前和循环阶段。
