信号肽酶切割位点的计算机辅助预测
Computer-assisted predictions of signal peptidase processing sites.
作者信息
Folz R J, Gordon J I
出版信息
Biochem Biophys Res Commun. 1987 Jul 31;146(2):870-7. doi: 10.1016/0006-291x(87)90611-5.
PMID:3304288
Abstract
Computer programs are presented which incorporate 2 different algorithms for predicting the site of signal peptide cleavage for eukaryotic preproteins. These programs can be used to identify sites of signal peptidase cleavage of putative preproteins to facilitate the design and interpretation of signal peptide mutagenesis experiments, and to engineer artificial prepolypeptides.
摘要
本文展示了计算机程序，其包含两种不同算法，用于预测真核生物前体蛋白信号肽切割位点。这些程序可用于识别假定前体蛋白的信号肽酶切割位点，以促进信号肽诱变实验的设计和解读，并构建人工前体多肽。
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