Orozco Virginia, Balasubramanian Sriram, Singh Anita
Drexel University, School of Biomedical Engineering, Science and Health Systems, Philadelphia, Pennsylvania, USA.
Widener University, School of Engineering, Chester, Pennsylvania, USA.
Neurol Neurobiol (Tallinn). 2020;3(2). doi: 10.31487/j.nnb.2020.02.12. Epub 2020 Jun 5.
Despite improvements in obstetric care, neonatal brachial plexus palsy continues to significantly impact infants' lives worldwide, with an incidence of 1 to 4 per 1000 live births. While a majority of affected infants recover spontaneously by three months, 20-30% suffer permanent functional deficits that significantly impair their quality of life. Anatomical complexity of the brachial plexus results in varying degrees of injury and pathological changes at multiple levels within the plexus. Current clinical diagnosis relies on electrodiagnostic techniques such as nerve conduction (i.e., motor and sensory) and electromyography studies. These techniques not only aid clinicians to differentiate between axonal and demyelinating lesions, evident by changes in signal shape and conduction, but also provide prognostic information in cases of brachial plexus injuries. The presented study offers a comprehensive review of existing literature on electrodiagnostic techniques employed for assessing neonatal brachial plexus injuries.
尽管产科护理有所改善,但新生儿臂丛神经麻痹在全球范围内仍继续对婴儿的生活产生重大影响,活产婴儿的发病率为每1000例中有1至4例。虽然大多数受影响的婴儿在三个月内会自发恢复,但20%至30%的婴儿会遭受永久性功能缺陷,严重损害他们的生活质量。臂丛神经的解剖复杂性导致神经丛内多个层面出现不同程度的损伤和病理变化。目前的临床诊断依赖于神经传导(即运动和感觉)和肌电图研究等电诊断技术。这些技术不仅有助于临床医生通过信号形状和传导的变化区分轴索性和脱髓鞘性病变,还能为臂丛神经损伤病例提供预后信息。本研究对用于评估新生儿臂丛神经损伤的电诊断技术的现有文献进行了全面综述。