Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, Yunnan, China.
Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment of the People's Republic of China, Nanjing, China.
Nat Prod Res. 2022 May;36(9):2292-2299. doi: 10.1080/14786419.2020.1830393. Epub 2020 Oct 12.
Four new triterpene glucosides () were isolated from the 90% ethanol extract of , together with five known compounds (). The structures of the new compounds were elucidated by comprehensive spectroscopic analysis including HRESIMS, IR, 1 D and 2 D NMR analysis. All isolates were assayed for their α-glucosidase inhibitory activity. Compound showed remarkable α-glucosidase inhibitory activity with an IC value of 0.31 μM, and the triterpene glycosides (-) exhibited moderate α-glucosidase inhibitory activity.
从 90%乙醇提取物中分离得到四个新的三萜糖苷（），并与五个已知化合物（）一起。通过综合光谱分析，包括 HRESIMS、IR、1D 和 2D NMR 分析，阐明了新化合物的结构。所有分离物均进行了 α-葡萄糖苷酶抑制活性测定。化合物显示出显著的α-葡萄糖苷酶抑制活性，IC 值为 0.31 μM，三萜糖苷（-）表现出中等的α-葡萄糖苷酶抑制活性。
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