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使用乙烯-乙烯醇共聚物(Onyx)治疗Ⅱ型内漏的结果。

Outcomes of Type II Endoleak Treatment Using Ethylene Vinyl Alcohol Copolymer (Onyx).

作者信息

Nuckles Brandon, Nadal Luis, Berger Andrea, Salzler Gregory, Elmore James R, Ryer Evan J

机构信息

Department of Endovascular and Vascular Surgery, 21599Geisinger Medical Center, Danville, PA, USA.

Department of Interventional Radiology, Geisinger Medical Center, Danville, PA, USA.

出版信息

Vasc Endovascular Surg. 2021 Jan;55(1):50-57. doi: 10.1177/1538574420964644. Epub 2020 Oct 12.

Abstract

INTRODUCTION

This study reports our experience with the use of an ethylene vinyl alcohol copolymer (Onyx™) for the treatment of type II endoleak after endovascular repair of abdominal aortic aneurysms (EVAR) in comparison to coils and cyanoacrylate glue.

METHODS

Clinical data of all patients treated for type II endoleak following EVAR between 2009 and 2017 were retrospectively analyzed. Abdominal aortic aneurysm (AAA) diameter and AAA sac volume during follow-up were measured using computed tomography angiography (CTA). Treatment failure variables were created for the change in sac diameter and volume. An increase in sac diameter ≥ 5 mm was considered a failure, as was an increase ≥ 10% in AAA sac volume.

RESULTS

35 patients underwent treatment for a persistent type II endoleak following EVAR. Of these patients, 18 (51.4%) were treated with Onyx and 17 (48.6%) were treated with coils ± cyanoacrylate glue embolization. There were no significant differences between the 2 groups with regard to demographics. The average volume of Onyx used per treatment was 13.4 ml (range 4.5 ml- 39 ml). There was no difference in efficacy between the Onyx and non-Onyx group. Complications were limited to 1 non-target embolization without significant clinical sequelae.

CONCLUSIONS

Ethylene vinyl alcohol copolymer (Onyx™) embolization is similarly effective compared to traditional cyanoacrylate glue or coil embolization in the treatment of type II endoleak after EVAR.

摘要

引言

本研究报告了我们使用乙烯-乙烯醇共聚物(Onyx™)治疗腹主动脉瘤血管内修复术(EVAR)后Ⅱ型内漏的经验,并与弹簧圈和氰基丙烯酸酯胶进行了比较。

方法

回顾性分析2009年至2017年间所有接受EVAR术后Ⅱ型内漏治疗患者的临床资料。随访期间使用计算机断层扫描血管造影(CTA)测量腹主动脉瘤(AAA)直径和AAA瘤腔体积。为瘤腔直径和体积的变化设定治疗失败变量。瘤腔直径增加≥5mm被视为治疗失败,AAA瘤腔体积增加≥10%也被视为治疗失败。

结果

35例患者接受了EVAR术后持续性Ⅱ型内漏的治疗。其中,18例(51.4%)接受了Onyx治疗,17例(48.6%)接受了弹簧圈±氰基丙烯酸酯胶栓塞治疗。两组在人口统计学方面无显著差异。每次治疗使用Onyx的平均体积为13.4ml(范围4.5ml - 39ml)。Onyx组和非Onyx组在疗效上无差异。并发症仅限于1例非靶血管栓塞,无明显临床后遗症。

结论

在治疗EVAR术后Ⅱ型内漏方面,乙烯-乙烯醇共聚物(Onyx™)栓塞与传统氰基丙烯酸酯胶或弹簧圈栓塞同样有效。

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