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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Smolin L A, Grosvenor M B, Handelsman D J, Brasel J A

Br J Nutr. 1987 Jul;58(1):13-21. doi: 10.1079/bjn19870064.

Adipose tissue lipoprotein lipase (EC 3.1.1.34; AT-LPL), a rate-limiting enzyme in triglyceride storage in adipose tissue, is hormonally regulated and may be important in the maintenance of obesity. 2. In twelve obese women, AT-LPL activity was measured before weight loss, during weight loss and after 1 and 2 weeks of weight maintenance on either a high-carbohydrate or a high-protein diet. 3. When related to tissue weight, AT-LPL activity during the 2 weeks of weight maintenance was higher than the initial AT-LPL activity; there was no difference when activity was expressed per cell. 4. Changes in AT-LPL activity were not affected by diet composition. AT-LPL activity correlated with insulin levels and a change in insulin sensitivity of AT-LPL was observed after weight loss.

脂肪组织脂蛋白脂肪酶（EC 3.1.1.34；AT-LPL）是脂肪组织中甘油三酯储存的限速酶，受激素调节，可能在肥胖的维持中起重要作用。2. 在12名肥胖女性中，测量了她们在减肥前、减肥期间以及在高碳水化合物或高蛋白饮食下维持体重1周和2周后的AT-LPL活性。3. 与组织重量相关时，维持体重2周期间的AT-LPL活性高于初始AT-LPL活性；以每细胞表示活性时则无差异。4. AT-LPL活性的变化不受饮食组成的影响。AT-LPL活性与胰岛素水平相关，减肥后观察到AT-LPL的胰岛素敏感性发生了变化。

Smolin L A, Grosvenor M B, Handelsman D J, Brasel J A

Br J Nutr. 1987 Jul;58(1):13-21. doi: 10.1079/bjn19870064.

Adipose tissue lipoprotein lipase (EC 3.1.1.34; AT-LPL), a rate-limiting enzyme in triglyceride storage in adipose tissue, is hormonally regulated and may be important in the maintenance of obesity. 2. In twelve obese women, AT-LPL activity was measured before weight loss, during weight loss and after 1 and 2 weeks of weight maintenance on either a high-carbohydrate or a high-protein diet. 3. When related to tissue weight, AT-LPL activity during the 2 weeks of weight maintenance was higher than the initial AT-LPL activity; there was no difference when activity was expressed per cell. 4. Changes in AT-LPL activity were not affected by diet composition. AT-LPL activity correlated with insulin levels and a change in insulin sensitivity of AT-LPL was observed after weight loss.

脂肪组织脂蛋白脂肪酶（EC 3.1.1.34；AT-LPL）是脂肪组织中甘油三酯储存的限速酶，受激素调节，可能在肥胖的维持中起重要作用。2. 在12名肥胖女性中，测量了她们在减肥前、减肥期间以及在高碳水化合物或高蛋白饮食下维持体重1周和2周后的AT-LPL活性。3. 与组织重量相关时，维持体重2周期间的AT-LPL活性高于初始AT-LPL活性；以每细胞表示活性时则无差异。4. AT-LPL活性的变化不受饮食组成的影响。AT-LPL活性与胰岛素水平相关，减肥后观察到AT-LPL的胰岛素敏感性发生了变化。