Bell C
Blood Vessels. 1987;24(5):234-9. doi: 10.1159/000158699.
Dopamine represents 1-5% of the total catecholamine pool in sympathetically innervated tissues. A substantial proportion of this dopamine is located in vesicles, and nerve activation results in liberation of dopamine as well as noradrenaline. In certain tissues, there is neurochemical and functional evidence for the existence in addition of separate populations of dopaminergic sympathetic nerves. Some of the unsolved questions relating to the neural release of dopamine are: Is intravesicular dopamine in noradrenergic nerves a stable storage pool? Do noradrenergic nerves release dopamine and noradrenaline by identical mechanisms? What physiological roles do the sympathetic dopaminergic nerves play? What are the diagnostic and therapeutic implications of neural dopamine release?
多巴胺占交感神经支配组织中儿茶酚胺总量的1%-5%。该多巴胺的很大一部分存在于囊泡中，神经激活会导致多巴胺以及去甲肾上腺素的释放。在某些组织中，有神经化学和功能证据表明还存在独立的多巴胺能交感神经群体。一些与多巴胺神经释放相关的未解决问题包括：去甲肾上腺素能神经中的囊泡内多巴胺是一个稳定的储存库吗？去甲肾上腺素能神经通过相同机制释放多巴胺和去甲肾上腺素吗？交感多巴胺能神经发挥什么生理作用？神经多巴胺释放有哪些诊断和治疗意义？
