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尼日利亚奥贡州阿贝奥库塔的动物 handlers 中病毒性肝炎的高血清流行率。

High seroprevalence of viral hepatitis among animal handlers in Abeokuta, Ogun State, Nigeria.

机构信息

Department of Medical Laboratory Science, Babcock University, Ilishan Remo, Nigeria.

Department of Medical Microbiology and Parasitology, Ladoke Akintola University of Technology, Ogbomoso, Nigeria.

出版信息

J Immunoassay Immunochem. 2021 Jan 2;42(1):34-47. doi: 10.1080/15321819.2020.1814810. Epub 2020 Oct 12.

Abstract

Viral hepatitis is a deadly disease which can manifest as acute, chronic, hepatocellular carcinoma, and liver failure. Information about hepatitis is scarce among animal handlers. Due to Federal Government of Nigeria diversification programmes, many people are now involved in animal farming which can make them susceptible to viral hepatitis. This study aimed at determining the prevalence of Hepatitis B, C, and E viruses among animal handlers in Abeokuta, southwestern Nigerian. A total of 156 subjects were recruited for the study. Sociodemographic and risks factors data were fetched from subjects using interviewer-administered questionnaire. Blood samples were collected via venepuncture and tested for HCV, HBV, and HEV using ELISA technique. Results were analyzed using SPSS software version 21.0 and value ≤ 0.05 was considered significant. The prevalence of HCV, HBV, and HEV were 46 (29.5%), 20 (12.8%), and 4 (2.6%) respectively while 6 (3.8%), 1 (0.6%), and 1 (0.6%) had co-infection of HBV-HCV, HBV-HEV, and HCV- HEV respectively. This study concludes that there is high prevalence of hepatitis C and B viruses among animal handlers in Abeokuta, Ogun state which is of significant public health problem, warranting further attention and research.

摘要

病毒性肝炎是一种致命的疾病,可表现为急性、慢性、肝细胞癌和肝功能衰竭。动物 handlers 对肝炎的信息知之甚少。由于尼日利亚联邦政府的多元化计划,现在许多人从事动物养殖,这使他们容易感染病毒性肝炎。本研究旨在确定在 Abeokuta 西南部的尼日利亚动物 handlers 中乙型肝炎、丙型肝炎和戊型肝炎病毒的流行情况。共招募了 156 名受试者参加这项研究。使用访谈式调查问卷从受试者中获取社会人口统计学和风险因素数据。通过静脉穿刺采集血液样本,并使用 ELISA 技术检测 HCV、HBV 和 HEV。使用 SPSS 软件版本 21.0 分析结果, 值≤0.05 被认为具有统计学意义。HCV、HBV 和 HEV 的流行率分别为 46(29.5%)、20(12.8%)和 4(2.6%),而 HBV-HCV、HBV-HEV 和 HCV-HEV 的合并感染率分别为 6(3.8%)、1(0.6%)和 1(0.6%)。本研究得出结论,在奥贡州 Abeokuta 的动物 handlers 中,丙型和乙型肝炎病毒的流行率很高,这是一个重大的公共卫生问题,值得进一步关注和研究。

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