Health Service & Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Department of Psychiatry, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
Early Interv Psychiatry. 2021 Oct;15(5):1104-1114. doi: 10.1111/eip.13060. Epub 2020 Oct 13.
The evidence of the effectiveness and cost-effectiveness of early intervention for psychosis (EIP) services has motivated their implementation worldwide. However, complex interventions of such EIP services require local adaptations to successfully match population needs and cultural differences. Latin America is a heterogenous region where EIP services are progressively being adopted. Our aim is to map such initiatives in the region with a focus on implementation outcomes.
A scoping review following the Preferred Reporting Items for Systematic review and Meta-Analysis extension for Scoping Reviews guidelines was conducted. International and regional databases were searched for publications describing EIP programmes in the region. Besides mapping the services, we described implementation outcomes based on the Standards for Reporting Implementation Studies Checklist.
Ten articles describing seven EIP initiatives from the region were found. Four countries were represented: Argentina, Brazil, Chile and Mexico. The implementation outcomes reporting was heterogenous, although it was possible to ascertain EIP services are feasible and adequate for the region's context. Also, there is some evidence of effectiveness in terms of reducing hospitalizations and improving symptoms. Information about fidelity measures was scarce and there was no information about costs or cost-effectiveness.
Only a small proportion of Latin American countries have adopted EIP services. Although these programmes seem to be feasible and effective, data on other implementation outcomes, such as fidelity, cultural appropriateness, cost-effectiveness and affordability are not available. This might in part explain why this effective approach has not been yet scaled-up at nationwide levels.
精神分裂症早期干预(EIP)服务的有效性和成本效益证据促使其在全球范围内得到实施。然而,此类 EIP 服务的复杂干预措施需要进行本土化调整,以成功满足人群需求和文化差异。拉丁美洲是一个多样化的地区,正在逐步采用 EIP 服务。我们的目标是绘制该地区的此类举措图,重点关注实施结果。
根据系统评价和荟萃分析扩展的首选报告项目,对范围综述指南进行了综述。搜索了国际和区域数据库,以查找描述该地区 EIP 计划的出版物。除了绘制服务地图外,我们还根据实施研究报告标准清单描述了实施结果。
发现了 10 篇描述该地区 7 项 EIP 举措的文章。代表了四个国家:阿根廷、巴西、智利和墨西哥。实施结果的报告存在差异,但可以确定 EIP 服务对于该地区的背景是可行和适当的。此外,在减少住院和改善症状方面有一些有效性的证据。关于保真度措施的信息很少,也没有关于成本或成本效益的信息。
只有少数拉丁美洲国家采用了 EIP 服务。尽管这些方案似乎是可行和有效的,但关于其他实施结果的数据,如保真度、文化适宜性、成本效益和负担能力,尚不可用。这可能部分解释了为什么这种有效的方法尚未在全国范围内扩大规模。