兔皮肤同种异体移植中对环孢素耐药的效应细胞。
Cyclosporine resistant effector cells in rabbit skin allografts.
作者信息
Gratwohl A, Riederer I, Walstra K, Baldomero H, Speck B
出版信息
Experientia. 1987 Aug 15;43(8):910-2. doi: 10.1007/BF01951663.
PMID:3305068
Abstract
Histoincompatible skin grafts in rabbits treated with cyclosporine can permanently engraft but show a transient mononuclear cellular infiltrate. This transient cyclosporine-resistant infiltrate consists of cells which are sensitive to steroids, radiation and cryopreservation. They have the same ACM-1 phenotype and the same characteristics as cyclosporine-sensitive cells.
摘要
用环孢素治疗的兔子体内，组织不相容的皮肤移植可以永久植入，但会出现短暂的单核细胞浸润。这种短暂的对环孢素耐药的浸润由对类固醇、辐射和冷冻保存敏感的细胞组成。它们具有与环孢素敏感细胞相同的ACM-1表型和相同的特征。
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